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  4. Recombinant Human Interleukin-17D (IL17D)

Recombinant Human Interleukin-17D (IL17D)

  • 中文名称：
    人IL17D重组蛋白
  • 货号：
    CSB-YP848386HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人IL17D重组蛋白
  • 货号：
    CSB-EP848386HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人IL17D重组蛋白
  • 货号：
    CSB-EP848386HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人IL17D重组蛋白
  • 货号：
    CSB-BP848386HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人IL17D重组蛋白
  • 货号：
    CSB-MP848386HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    IL 17D; IL 22; IL 27; IL-17D; IL-27; IL17D; IL17D_HUMAN; IL27; Interleukin 17D ; Interleukin 27; Interleukin-17D; Interleukin-27
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    16-202
  • 氨基酸序列
    AGAPR AGRRPARPRG CADRPEELLE QLYGRLAAGV LSAFHHTLQL GPREQARNAS CPAGGRPADR RFRPPTNLRS VSPWAYRISY DPARYPRYLP EAYCLCRGCL TGLFGEEDVR FRSAPVYMPT VVLRRTPACA GGRSVYTEAY VTIPVGCTCV PEPEKDADSI NSSIDKQGAK LLLGPNDAPA GP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Induces expression of IL6, CXCL8/IL8, and CSF2/GM-CSF from endothelial cells.
  • 基因功能参考文献：
    1. Nrf2 Induces IL-17D to mediate tumor and virus surveillance. PMID: 27545889
    2. Study of the expression of IL-17 provides theoretical support for the clinical treatment and prognosis prediction of ovarian epithelial tumor. PMID: 28685546
    3. Utilizing gene microarray analysis, s found the cytokine interleukin 17D (IL-17D) was highly expressed in certain unedited tumors. PMID: 24794441
    4. These experiments were designed to investigate the effects of IL-17 upon the phenotype and function of human Natural Killer (NK) cells. PMID: 23490420
    5. IL-27 priming results in enhanced lipopolysaccharide-induced IL-6, tumor necrosis factor (TNF)-alpha, macrophage inflammatory protein (MIP)-1alpha, and MIP-1beta expression in human primary monocytes. PMID: 22156348
    6. IL-17D stimulates production of cytokines in endothelial cells in vitro and suppresses proliferation of myeloid progenitors in colony formation assays. PMID: 12097364

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    IL-17 family
  • 组织特异性：
    Expressed preferentially in adipose, skeletal muscle and CNS.
  • 数据库链接：

    HGNC: 5984

    OMIM: 607587

    KEGG: hsa:53342

    STRING: 9606.ENSP00000302924

    UniGene: Hs.655142