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HPCAL1 Antibody

  • 货号：
    CSB-PA02269A0Rb
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA02269A0Rb at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA02269A0Rb at dilution of 1:100
    • Immunofluorescent analysis of PC-3 cells using CSB-PA02269A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) HPCAL1 Polyclonal antibody
  • Uniprot No.：
    P37235
  • 基因名：
    HPCAL1
  • 别名：
    BDR1 antibody; Calcium binding protein BDR1 antibody; Calcium-binding protein BDR-1 antibody; hippocalcin like 1 antibody; Hippocalcin-like protein 1 antibody; HLP2 antibody; HPCAL1 antibody; HPCAL1 protein antibody; HPCL1_HUMAN antibody; REM-1 antibody; VILIP-3 antibody; Visinin like protein 3 antibody; Visinin-like protein 3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Hippocalcin-like protein 1 protein (2-193AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，HPCAL1 Antibody (CSB-PA02269A0Rb)，的标记方式是Non-conjugated。对于HPCAL1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA02269B0Rb HPCAL1 Antibody, HRP conjugated ELISA
    FITC CSB-PA02269C0Rb HPCAL1 Antibody, FITC conjugated
    Biotin CSB-PA02269D0Rb HPCAL1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May be involved in the calcium-dependent regulation of rhodopsin phosphorylation.
  • 基因功能参考文献：
    1. The myristoylated VILIP-3 protein structure determined in this study is quite different. PMID: 27820860
    2. Secreted HPCAL1 protein in the plasma dropped dramatically in hepatocellular carcinoma patients relative to controls. PMID: 26659654
    3. Results show that in the presence of calcium, N-myristoylation significantly increases the kinetic rate of VILIP adsorption to the membrane. PMID: 25019684
    4. HPCAL1 did not appreciably influence the ability of WT PHOX2B. PMID: 23873030
    5. visinin-like protein-3 interacts with microsomal cytochrome b5 in a Ca2+-dependent manner PMID: 14739275
    6. The interaction of human VILIP1 and VILIP3 with divalent cations was explored using circular dichroism and fluorescence measurement. PMID: 16703469
    7. VILIP-3 immunostaining was found to be reduced in Alzheimer brains; immunoreactive material was detected in close association with amyloid plaques and neurofibrillar tangles, typical pathologic hallmarks of AD PMID: 11173883

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  • 亚细胞定位：
    Membrane; Lipid-anchor.
  • 蛋白家族：
    Recoverin family
  • 数据库链接：

    HGNC: 5145

    OMIM: 600207

    KEGG: hsa:3241

    STRING: 9606.ENSP00000310749

    UniGene: Hs.580427