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  4. Recombinant Human Hippocalcin-like protein 1 (HPCAL1)

Recombinant Human Hippocalcin-like protein 1 (HPCAL1)

  • 中文名称：
    人HPCAL1重组蛋白
  • 货号：
    CSB-YP010695HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人HPCAL1重组蛋白
  • 货号：
    CSB-EP010695HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人HPCAL1重组蛋白
  • 货号：
    CSB-EP010695HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人HPCAL1重组蛋白
  • 货号：
    CSB-BP010695HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人HPCAL1重组蛋白
  • 货号：
    CSB-MP010695HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    HPCAL1
  • Uniprot No.：
  • 别名：
    BDR1; Calcium binding protein BDR1; Calcium-binding protein BDR-1; hippocalcin like 1; Hippocalcin-like protein 1; HLP2; HPCAL1; HPCAL1 protein; HPCL1_HUMAN; REM-1; VILIP-3; Visinin like protein 3; Visinin-like protein 3
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-193
  • 氨基酸序列
    GKQNSKLRP EVLQDLRENT EFTDHELQEW YKGFLKDCPT GHLTVDEFKK IYANFFPYGD ASKFAEHVFR TFDTNGDGTI DFREFIIALS VTSRGKLEQK LKWAFSMYDL DGNGYISRSE MLEIVQAIYK MVSSVMKMPE DESTPEKRTD KIFRQMDTNN DGKLSLEEFI RGAKSDPSIV RLLQCDPSSA SQF
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May be involved in the calcium-dependent regulation of rhodopsin phosphorylation.
  • 基因功能参考文献：
    1. The myristoylated VILIP-3 protein structure determined in this study is quite different. PMID: 27820860
    2. Secreted HPCAL1 protein in the plasma dropped dramatically in hepatocellular carcinoma patients relative to controls. PMID: 26659654
    3. Results show that in the presence of calcium, N-myristoylation significantly increases the kinetic rate of VILIP adsorption to the membrane. PMID: 25019684
    4. HPCAL1 did not appreciably influence the ability of WT PHOX2B. PMID: 23873030
    5. visinin-like protein-3 interacts with microsomal cytochrome b5 in a Ca2+-dependent manner PMID: 14739275
    6. The interaction of human VILIP1 and VILIP3 with divalent cations was explored using circular dichroism and fluorescence measurement. PMID: 16703469
    7. VILIP-3 immunostaining was found to be reduced in Alzheimer brains; immunoreactive material was detected in close association with amyloid plaques and neurofibrillar tangles, typical pathologic hallmarks of AD PMID: 11173883

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  • 亚细胞定位：
    Membrane; Lipid-anchor.
  • 蛋白家族：
    Recoverin family
  • 数据库链接：

    HGNC: 5145

    OMIM: 600207

    KEGG: hsa:3241

    STRING: 9606.ENSP00000310749

    UniGene: Hs.580427