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GNAS Antibody

  • 货号：
    CSB-PA352389LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Rat brain tissue, Mouse brain tissue
      All lanes: GNAS antibody at 3µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 46, 45, 112, 110, 78, 29 kDa
      Observed band size: 46 kDa
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA352389LA01HU at dilution of 1:100
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA352389LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品描述：

    The GNAS antibody is generated by immunizing rabbits with the full-length amino acids of the human GNAS protein. It is a polyclonal antibody and occurs as an unconjugated IgG. Its purity is greater than 95% using protein G purified. It shows cross-reactivity with human, mouse, and rat GNAS protein. This GNAS antibody is available for use in ELISA, WB, IHC, and IF applications. The target protein GNAS is the stimulatory alpha subunit of the guanine nucleotide-binding protein (G protein), which is a widely expressed signaling protein essential for the actions of many hormones and other endogenous molecules.

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) GNAS Polyclonal antibody
  • Uniprot No.：
    P63092
  • 基因名：
  • 别名：
    Adenylate cyclase-stimulating G alpha protein antibody; AHO antibody; alternative gene product encoded by XL-exon antibody; C20orf45 antibody; extra large alphas protein antibody; GNAS antibody; GNAS complex locus antibody; GNAS1 antibody; GNAS1 gene, formerly antibody; GNAS1, formerly antibody; GNAS2_HUMAN antibody; GPSA antibody; GSA antibody; GSP antibody; guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 antibody; guanine nucleotide regulatory protein antibody; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short antibody; guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas antibody; NESP antibody; neuroendocrine secretory protein antibody; PHP1A antibody; PHP1B antibody; PHP1C antibody; POH antibody; protein ALEX antibody; secretogranin VI antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human Guanine nucleotide-binding protein G(s) subunit alpha isoforms short protein (1-394AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，GNAS Antibody (CSB-PA352389LA01HU)，的标记方式是Non-conjugated。对于GNAS Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA352389LB01HU GNAS Antibody, HRP conjugated ELISA
    FITC CSB-PA352389LC01HU GNAS Antibody, FITC conjugated
    Biotin CSB-PA352389LD01HU GNAS Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2.
  • 相关疾病：
    Albright hereditary osteodystrophy (AHO); Pseudohypoparathyroidism 1A (PHP1A); McCune-Albright syndrome (MAS); Progressive osseous heteroplasia (POH); ACTH-independent macronodular adrenal hyperplasia 1 (AIMAH1); Pseudohypoparathyroidism 1B (PHP1B); GNAS hyperfunction (GNASHYP); Pseudohypoparathyroidism 1C (PHP1C)
  • 亚细胞定位：
    Cell membrane; Lipid-anchor.
  • 蛋白家族：
    G-alpha family, G(s) subfamily
  • 数据库链接：

    HGNC: 4392

    OMIM: 103580

    KEGG: hsa:2778

    UniGene: Hs.125898