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GNAS Antibody

  • 货号：
    CSB-PA247539
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA247539(GNAS Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 30 μg, Lane: Mouse brain tissue, Primary antibody: CSB-PA247539(GNAS Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds
  • 其他：

产品详情

  • Uniprot No.：
    P63092
  • 基因名：
  • 别名：
    Adenylate cyclase-stimulating G alpha protein antibody; AHO antibody; alternative gene product encoded by XL-exon antibody; C20orf45 antibody; extra large alphas protein antibody; GNAS antibody; GNAS complex locus antibody; GNAS1 antibody; GNAS1 gene, formerly antibody; GNAS1, formerly antibody; GNAS2_HUMAN antibody; GPSA antibody; GSA antibody; GSP antibody; guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 antibody; guanine nucleotide regulatory protein antibody; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short antibody; guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas antibody; NESP antibody; neuroendocrine secretory protein antibody; PHP1A antibody; PHP1B antibody; PHP1C antibody; POH antibody; protein ALEX antibody; secretogranin VI antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human GNAS
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2.
  • 相关疾病：
    Albright hereditary osteodystrophy (AHO); Pseudohypoparathyroidism 1A (PHP1A); McCune-Albright syndrome (MAS); Progressive osseous heteroplasia (POH); ACTH-independent macronodular adrenal hyperplasia 1 (AIMAH1); Pseudohypoparathyroidism 1B (PHP1B); GNAS hyperfunction (GNASHYP); Pseudohypoparathyroidism 1C (PHP1C)
  • 亚细胞定位：
    Cell membrane; Lipid-anchor.
  • 蛋白家族：
    G-alpha family, G(s) subfamily
  • 数据库链接：

    HGNC: 4392

    OMIM: 103580

    KEGG: hsa:2778

    UniGene: Hs.125898