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FZR1 Antibody

  • 货号：
    CSB-PA845079XA01DOA
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes: FZR1 Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 34 kDa
      Observed band size: 34 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) FZR1 Polyclonal antibody
  • Uniprot No.：
    Q8VZS9
  • 基因名：
  • 别名：
    Protein FIZZY-RELATED 1 (Cell cycle switch protein CCS52A2) FZR1 CCS52A2 CDH1-1 At4g11920 T26M18.130
  • 宿主：
    Rabbit
  • 反应种属：
    Arabidopsis thaliana
  • 免疫原：
    Recombinant Arabidopsis thaliana FZR1 protein (1-280aa)
  • 免疫原种属：
    Arabidopsis thaliana (Mouse-ear cress)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Activator protein that regulates the ubiquitin ligase activity and substrate specificity of the anaphase promoting complex/cyclosome (APC/C). Required for meristem organization and maintenance of quiescent center identity and stem cells.
  • 基因功能参考文献：
    1. The data illustrate cooperative activity of the APC/C(CCS52A1) and APC/C(CCS52A2) complexes during root and trichome development, but functional interdependency during leaf development. Furthermore, we found APC/C(CCS52A1) activity to control CCS52A2 expression. We conclude that interdependency of CCS52A-controlled APC/C activity is controlled in a tissue-specific manner. PMID: 28698355
    2. A ccs52A2 mutation did not affect the level or pattern of cyclin B1;1 expression, indicating that CCS52A2 does not mediate the effect of auxin on cyclin B1;1. PMID: 26662023
    3. Findings support both complementary and dose-dependent actions for the Arabidopsis CCS52A isoforms in plant development and demonstrate that elevated ectopic CCS52A expression positively correlates with organ size, opening a route to higher biomass production. [CCS52A2] PMID: 23528034
    4. The CCS52A2 gene is a mediator that functions together with meristematic genes to regulate meristem organization. PMID: 22873486
    5. CCS52A2 acts directly in the distal region of the root meristem to control identity of the quiescent center (QC) cells and stem cell maintenance. PMID: 19553203

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    WD repeat CDC20/Fizzy family
  • 组织特异性：
    Expressed in the root tip, predominantly in the root cap, quiescent center cells, surrounding stem cells and columella.
  • 数据库链接：

    KEGG: ath:AT4G11920

    STRING: 3702.AT4G11920.1

    UniGene: At.27160