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  4. Recombinant Arabidopsis thaliana Protein FIZZY-RELATED 1 (FZR1)

Recombinant Arabidopsis thaliana Protein FIZZY-RELATED 1 (FZR1)

  • 货号：
    CSB-YP845079DOA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP845079DOA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP845079DOA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP845079DOA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP845079DOA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    FZR1; CCS52A2; CDH1-1; At4g11920; T26M18.130; Protein FIZZY-RELATED 1; Cell cycle switch protein CCS52A2
  • 种属：
    Arabidopsis thaliana (Mouse-ear cress)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-475
  • 氨基酸序列
    MEEDESTTPK KKSDSQLNLP PSMNRPTVSL ESRINRLIDS NHYHSPSKPI YSDRFIPSRS GSNFALFDLA SSSPNKKDGK EDGAGSYASL LKTALFGPVT PEKSDVVNGF SPSGNIFRFK TETQRSLNLY PPFDSDVVSG VSPSPVKSPR KILRSPYKVL DAPALQDDFY LNLVDWSAQN VLAVGLGNCV YLWNACSSKV TKLCDLGVDE TVCSVGWALR GTHLAIGTSS GTVQIWDVLR CKNIRTMEGH RLRVGALAWS SSVLSSGSRD KSILQRDIRT QEDHVSKLKG HKSEICGLKW SSDNRELASG GNDNKLFVWN QHSTQPVLRF CEHAAAVKAI AWSPHHFGLL ASGGGTADRC IRFWNTTTNT HLNCVDTNSQ VCNLVWSKNV NELVSTHGYS QNQIIVWKYP TMSKLATLTG HSYRVLYLAV SPDGQTIVTG AGDETLRFWN VFPSPKSQSR ESEIGALSFG RTTIR
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Activator protein that regulates the ubiquitin ligase activity and substrate specificity of the anaphase promoting complex/cyclosome (APC/C). Required for meristem organization and maintenance of quiescent center identity and stem cells.
  • 基因功能参考文献：
    1. The data illustrate cooperative activity of the APC/C(CCS52A1) and APC/C(CCS52A2) complexes during root and trichome development, but functional interdependency during leaf development. Furthermore, we found APC/C(CCS52A1) activity to control CCS52A2 expression. We conclude that interdependency of CCS52A-controlled APC/C activity is controlled in a tissue-specific manner. PMID: 28698355
    2. A ccs52A2 mutation did not affect the level or pattern of cyclin B1;1 expression, indicating that CCS52A2 does not mediate the effect of auxin on cyclin B1;1. PMID: 26662023
    3. Findings support both complementary and dose-dependent actions for the Arabidopsis CCS52A isoforms in plant development and demonstrate that elevated ectopic CCS52A expression positively correlates with organ size, opening a route to higher biomass production. [CCS52A2] PMID: 23528034
    4. The CCS52A2 gene is a mediator that functions together with meristematic genes to regulate meristem organization. PMID: 22873486
    5. CCS52A2 acts directly in the distal region of the root meristem to control identity of the quiescent center (QC) cells and stem cell maintenance. PMID: 19553203

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    WD repeat CDC20/Fizzy family
  • 组织特异性：
    Expressed in the root tip, predominantly in the root cap, quiescent center cells, surrounding stem cells and columella.
  • 数据库链接：

    KEGG: ath:AT4G11920

    STRING: 3702.AT4G11920.1

    UniGene: At.27160