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ENTPD3 Antibody

  • 货号：
    CSB-PA007692LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA007692LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA007692LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA007692LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ENTPD3 Polyclonal antibody
  • Uniprot No.：
    O75355
  • 基因名：
    ENTPD3
  • 别名：
    ATPDase antibody; CD39 antigen like 3 antibody; CD39 antigen-like 3 antibody; CD39 like 3 antibody; CD39L3 antibody; Ecto apyrase antibody; Ecto ATP diphosphohydrolase antibody; Ecto-apyrase 3 antibody; Ecto-ATP diphosphohydrolase 3 antibody; Ecto-ATPase 3 antibody; Ecto-ATPDase 3 antibody; Ectonucleoside triphosphate diphosphohydrolase 3 antibody; ENTP3_HUMAN antibody; ENTPD 3 antibody; ENTPD3 antibody; FLJ93839 antibody; HB 6 antibody; HB6 antibody; NTPDase 3 antibody; NTPDase3 antibody; OTTHUMP00000162079 antibody; OTTHUMP00000209227 antibody; OTTHUMP00000209228 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Ectonucleoside triphosphate diphosphohydrolase 3 protein (60-338AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ENTPD3 Antibody (CSB-PA007692LA01HU)，的标记方式是Non-conjugated。对于ENTPD3 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA007692LB01HU ENTPD3 Antibody, HRP conjugated ELISA
    FITC CSB-PA007692LC01HU ENTPD3 Antibody, FITC conjugated
    Biotin CSB-PA007692LD01HU ENTPD3 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Has a threefold preference for the hydrolysis of ATP over ADP.
  • 基因功能参考文献：
    1. NTPDase3 is the major ectonucleotidase in pancreatic beta-cells in multiple species and modulates insulin secretion by controlling activation of purinergic receptors. PMID: 24085034
    2. NTPDase3 sequence revealed a high degree of structural fold similarity with a bacterial exopolyphosphatase PMID: 15966724
    3. efficiently inhibit the NTPDase3expressed in insulin secreting human pancreatic islet cells in situ PMID: 19120451
    4. Generation of a helical model for NTPDase3 suggests the importance of putative hydrogen bond interactions of conserved polar residues which are critical for enzyme expression, activity, and its susceptibility to membrane perturbations. PMID: 19743837
  • 亚细胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    GDA1/CD39 NTPase family
  • 组织特异性：
    Expressed in adult brain, pancreas, spleen and prostate. Moderate or low expression is seen in most tissues. Not expressed in liver and peripheral blood leukocytes.
  • 数据库链接：

    HGNC: 3365

    OMIM: 603161

    KEGG: hsa:956

    STRING: 9606.ENSP00000301825

    UniGene: Hs.441145