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ENTPD3 Antibody

  • 货号：
    CSB-PA007692GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    O75355
  • 基因名：
    ENTPD3
  • 别名：
    ATPDase antibody; CD39 antigen like 3 antibody; CD39 antigen-like 3 antibody; CD39 like 3 antibody; CD39L3 antibody; Ecto apyrase antibody; Ecto ATP diphosphohydrolase antibody; Ecto-apyrase 3 antibody; Ecto-ATP diphosphohydrolase 3 antibody; Ecto-ATPase 3 antibody; Ecto-ATPDase 3 antibody; Ectonucleoside triphosphate diphosphohydrolase 3 antibody; ENTP3_HUMAN antibody; ENTPD 3 antibody; ENTPD3 antibody; FLJ93839 antibody; HB 6 antibody; HB6 antibody; NTPDase 3 antibody; NTPDase3 antibody; OTTHUMP00000162079 antibody; OTTHUMP00000209227 antibody; OTTHUMP00000209228 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human ENTPD3
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Has a threefold preference for the hydrolysis of ATP over ADP.
  • 基因功能参考文献：
    1. NTPDase3 is the major ectonucleotidase in pancreatic beta-cells in multiple species and modulates insulin secretion by controlling activation of purinergic receptors. PMID: 24085034
    2. NTPDase3 sequence revealed a high degree of structural fold similarity with a bacterial exopolyphosphatase PMID: 15966724
    3. efficiently inhibit the NTPDase3expressed in insulin secreting human pancreatic islet cells in situ PMID: 19120451
    4. Generation of a helical model for NTPDase3 suggests the importance of putative hydrogen bond interactions of conserved polar residues which are critical for enzyme expression, activity, and its susceptibility to membrane perturbations. PMID: 19743837
  • 亚细胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    GDA1/CD39 NTPase family
  • 组织特异性：
    Expressed in adult brain, pancreas, spleen and prostate. Moderate or low expression is seen in most tissues. Not expressed in liver and peripheral blood leukocytes.
  • 数据库链接：

    HGNC: 3365

    OMIM: 603161

    KEGG: hsa:956

    STRING: 9606.ENSP00000301825

    UniGene: Hs.441145