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EEF1D Antibody

  • 货号：
    CSB-PA007431LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: EEF1D antibody at 2µg/ml + MCF-7 whole cell lysate
      Secondary
      Goat polyclonal to rabbit lgG at 1/15000 dilution
      Predicted band size: 32, 72, 29, 30 kDa
      Observed band size: 32 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) EEF1D Polyclonal antibody
  • Uniprot No.：
    P29692
  • 基因名：
    EEF1D
  • 别名：
    Antigen NY CO 4 antibody; Antigen NY-CO-4 antibody; EEF 1D antibody; EEF1D antibody; EF 1 delta antibody; EF 1D antibody; EF-1-delta antibody; EF1D antibody; EF1D_HUMAN antibody; Elongation factor 1 delta antibody; Elongation factor 1-delta antibody; eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) antibody; Eukaryotic translation elongation factor 1 delta antibody; FP1047 antibody; Guanine nucleotide exchange protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Elongation factor 1-delta protein (2-281AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，EEF1D Antibody (CSB-PA007431LA01HU)，的标记方式是Non-conjugated。对于EEF1D Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA007431LB01HU EEF1D Antibody, HRP conjugated ELISA
    FITC CSB-PA007431LC01HU EEF1D Antibody, FITC conjugated
    Biotin CSB-PA007431LD01HU EEF1D Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome.; Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE).
  • 基因功能参考文献：
    1. eukaryotic translation elongation factor 1delta knockdown in oral squamous cell carcinoma reduced cell proliferation and induced EMT (epithelial-mesenchymal transition) phenotypes PMID: 26823560
    2. Taken together, our data suggest EFF1D functions as a novel negative regulator of SIAH-1 PMID: 21633900
    3. overexpression is positively correlated with malignant transformation of 16HBE cells induced by CdC12, but is not correlated with DNA mutations PMID: 20514991
    4. These results further confirm that overexpression of TEF-1 delta is oncogenic and the antisense TEF-1 delta mRNA expression reverses its oncogenic potential. PMID: 12210501
    5. Interaction between HrHRF and EF-1delta taken with some of the recently published information concerning the TCTP (HrHRF) mentioned above suggest a possible intracellular role for TCTP/HrHRF. PMID: 15062873
    6. Increased EF-1 delta mRNA expression is associated with lymph node metastases and advanced disease stages in esophageal carcinoma PMID: 15199388
    7. Gain of 8q-mapped EF-1 delta is associated with adverse outcome in Medulloblastoma. PMID: 16968546
    8. Repression of deltaEF1 plays a key role in mediating BMP-6-induced transcriptional activation of E-cadherin in breast cancer cells. PMID: 17997862

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  • 亚细胞定位：
    [Isoform 2]: Nucleus.
  • 蛋白家族：
    EF-1-beta/EF-1-delta family
  • 组织特异性：
    Isoform 2 is specifically expressed in brain, cerebellum and testis.
  • 数据库链接：

    HGNC: 3211

    OMIM: 130592

    KEGG: hsa:1936

    STRING: 9606.ENSP00000391944

    UniGene: Hs.333388