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DUSP13 Antibody

  • 货号：
    CSB-PA693441
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA693441(DUSP13 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA693441(DUSP13 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q9UII6
  • 基因名：
    DUSP13
  • 别名：
    DUSP13 antibody; DUSP13B antibody; TMDPDual specificity protein phosphatase 13 isoform B antibody; DUSP13B antibody; EC 3.1.3.16 antibody; EC 3.1.3.48 antibody; Dual specificity phosphatase SKRP4 antibody; Testis- and skeletal-muscle-specific DSP antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human DUSP13
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Dual specificity phosphatase that dephosphorylates MAPK8/JNK and MAPK14/p38, but not MAPK1/ERK2, in vitro. Exhibits intrinsic phosphatase activity towards both phospho-seryl/threonyl and -tyrosyl residues, with similar specific activities in vitro.
  • 基因功能参考文献：
    1. data suggest an important role for DUSP13B in protection from external stress during spermatogenesis PMID: 21360282
    2. identified a gene on chromosome 10q22.2 using alternative ORFs to encode two distinct DSPs: the testis and skeletal muscle-specific TMDP and a novel muscle-restricted DSP(MDSP) PMID: 15252030
    3. Here, we report the crystal structure of human TMDP at a resolution of 2.4 A. In spite of high sequence similarity with other DSPs, the crystal structure of TMDP shows distinct structural motifs and surface propertie PMID: 17044055
  • 蛋白家族：
    Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily
  • 组织特异性：
    Highly expressed in the testis (at protein level). Also found in the skeletal muscle.
  • 数据库链接：

    HGNC: 19681

    OMIM: 613191

    STRING: 9606.ENSP00000452702

    UniGene: Hs.178170