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  4. Recombinant Human Dual specificity protein phosphatase 13 (DUSP13)

Recombinant Human Dual specificity protein phosphatase 13 (DUSP13)

  • 中文名称：
    人DUSP13重组蛋白
  • 货号：
    CSB-YP883436HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人DUSP13重组蛋白
  • 货号：
    CSB-EP883436HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人DUSP13重组蛋白
  • 货号：
    CSB-EP883436HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人DUSP13重组蛋白
  • 货号：
    CSB-BP883436HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人DUSP13重组蛋白
  • 货号：
    CSB-MP883436HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    DUSP13
  • Uniprot No.：
  • 别名：
    DUSP13; DUSP13B; TMDPDual specificity protein phosphatase 13 isoform B; DUSP13B; EC 3.1.3.16; EC 3.1.3.48; Dual specificity phosphatase SKRP4; Testis- and skeletal-muscle-specific DSP
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-198
  • 氨基酸序列
    MDSLQKQDLR RPKIHGAVQA SPYQPPTLAS LQRLLWVRQA ATLNHIDEVW PSLFLGDAYA ARDKSKLIQL GITHVVNAAA GKFQVDTGAK FYRGMSLEYY GIEADDNPFF DLSVYFLPVA RYIRAALSVP QGRVLVHCAM GVSRSATLVL AFLMICENMT LVEAIQTVQA HRNICPNSGF LRQLQVLDNR LGRETGRF
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Dual specificity phosphatase that dephosphorylates MAPK8/JNK and MAPK14/p38, but not MAPK1/ERK2, in vitro. Exhibits intrinsic phosphatase activity towards both phospho-seryl/threonyl and -tyrosyl residues, with similar specific activities in vitro.
  • 基因功能参考文献：
    1. data suggest an important role for DUSP13B in protection from external stress during spermatogenesis PMID: 21360282
    2. identified a gene on chromosome 10q22.2 using alternative ORFs to encode two distinct DSPs: the testis and skeletal muscle-specific TMDP and a novel muscle-restricted DSP(MDSP) PMID: 15252030
    3. Here, we report the crystal structure of human TMDP at a resolution of 2.4 A. In spite of high sequence similarity with other DSPs, the crystal structure of TMDP shows distinct structural motifs and surface propertie PMID: 17044055
  • 蛋白家族：
    Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily
  • 组织特异性：
    Highly expressed in the testis (at protein level). Also found in the skeletal muscle.
  • 数据库链接：

    HGNC: 19681

    OMIM: 613191

    STRING: 9606.ENSP00000452702

    UniGene: Hs.178170