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DNASE2B Antibody

  • 中文名称：
    DNASE2B兔多克隆抗体
  • 货号：
    CSB-PA841227LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: A549 whole cell lysate, Jurkat whole cell lysate, K562 whole cell lysate, HepG2 whole cell lysate, U87 whole cell lysate
      All lanes: DNASE2B antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 42, 18 kDa
      Observed band size: 42 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) DNASE2B Polyclonal antibody
  • Uniprot No.：
    Q8WZ79
  • 基因名：
    DNASE2B
  • 别名：
    DNASE2B antibody; DLADDeoxyribonuclease-2-beta antibody; EC 3.1.22.1 antibody; DNase II-like acid DNase antibody; DNase2-like acid DNase antibody; Deoxyribonuclease II beta antibody; DNase II beta antibody; Endonuclease DLAD antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Deoxyribonuclease-2-beta protein (68-281AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，DNASE2B Antibody (CSB-PA841227LA01HU)，的标记方式是Non-conjugated。对于DNASE2B Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA841227LB01HU DNASE2B Antibody, HRP conjugated ELISA
    FITC CSB-PA841227LC01HU DNASE2B Antibody, FITC conjugated
    Biotin CSB-PA841227LD01HU DNASE2B Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Hydrolyzes DNA under acidic conditions. Does not require divalent cations for activity. Participates in the degradation of nuclear DNA during lens cell differentiation.
  • 基因功能参考文献：
    1. HSF4 exerts its function on lens differentiation via positive regulation of DLAD expression. PMID: 23507146
    2. These data identify DNase 2 as the predominant DNase on the mammalian skin surface and indicate that its activity is primarily targeted to exogenous DNA. PMID: 21390259
    3. gene lie head-to-head with the urate oxidase gene PMID: 11700027
  • 亚细胞定位：
    Lysosome.
  • 蛋白家族：
    DNase II family
  • 组织特异性：
    Highly expressed in the eye lens and in salivary gland. Detected at lower levels in lung, prostate and lymph node. Isoform 2 is lung specific.
  • 数据库链接：

    HGNC: 28875

    OMIM: 608057

    KEGG: hsa:58511

    STRING: 9606.ENSP00000359699

    UniGene: Hs.129142