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  4. Recombinant Human Deoxyribonuclease-2-beta (DNASE2B)

Recombinant Human Deoxyribonuclease-2-beta (DNASE2B)

  • 中文名称：
    人DNASE2B重组蛋白
  • 货号：
    CSB-YP841227HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人DNASE2B重组蛋白
  • 货号：
    CSB-EP841227HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人DNASE2B重组蛋白
  • 货号：
    CSB-EP841227HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人DNASE2B重组蛋白
  • 货号：
    CSB-BP841227HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人DNASE2B重组蛋白
  • 货号：
    CSB-MP841227HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    DNASE2B
  • Uniprot No.：
  • 别名：
    DNASE2B; DLADDeoxyribonuclease-2-beta; EC 3.1.22.1; DNase II-like acid DNase; DNase2-like acid DNase; Deoxyribonuclease II beta; DNase II beta; Endonuclease DLAD
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    28-361
  • 氨基酸序列
    ATI SCRNEEGKAV DWFTFYKLPK RQNKESGETG LEYLYLDSTT RSWRKSEQLM NDTKSVLGRT LQQLYEAYAS KSNNTAYLIY NDGVPKPVNY SRKYGHTKGL LLWNRVQGFW LIHSIPQFPP IPEEGYDYPP TGRRNGQSGI CITFKYNQYE AIDSQLLVCN PNVYSCSIPA TFHQELIHMP QLCTRASSSE IPGRLLTTLQ SAQGQKFLHF AKSDSFLDDI FAAWMAQRLK THLLTETWQR KRQELPSNCS LPYHVYNIKA IKLSRHSYFS SYQDHAKWCI SQKGTKNRWT CIGDLNRSPH QAFRSGGFIC TQNWQIYQAF QGLVLYYESC K
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Hydrolyzes DNA under acidic conditions. Does not require divalent cations for activity. Participates in the degradation of nuclear DNA during lens cell differentiation.
  • 基因功能参考文献：
    1. HSF4 exerts its function on lens differentiation via positive regulation of DLAD expression. PMID: 23507146
    2. These data identify DNase 2 as the predominant DNase on the mammalian skin surface and indicate that its activity is primarily targeted to exogenous DNA. PMID: 21390259
    3. gene lie head-to-head with the urate oxidase gene PMID: 11700027
  • 亚细胞定位：
    Lysosome.
  • 蛋白家族：
    DNase II family
  • 组织特异性：
    Highly expressed in the eye lens and in salivary gland. Detected at lower levels in lung, prostate and lymph node. Isoform 2 is lung specific.
  • 数据库链接：

    HGNC: 28875

    OMIM: 608057

    KEGG: hsa:58511

    STRING: 9606.ENSP00000359699

    UniGene: Hs.129142