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Ccl12 Antibody

  • 货号：
    CSB-PA09139A0Rb
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Mus musculus (Mouse) Ccl12 Polyclonal antibody
  • Uniprot No.：
    Q62401
  • 基因名：
    Ccl12
  • 别名：
    C-C motif chemokine 12 antibody; Ccl12 antibody; CCL12_MOUSE antibody; Macrophage/monocyte Chemotactic Protein antibody; MCP-1-related chemokine antibody; MCP-5 antibody; Monocyte chemoattractant protein 5 antibody; Monocyte chemotactic protein 5 antibody; OTTMUSP00000000792 antibody; Scya12 antibody; Small inducible cytokine A12 antibody; Small-inducible cytokine A12 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Mouse
  • 免疫原：
    Recombinant Mouse C-C motif chemokine 12 ptotein (23-104AA)
  • 免疫原种属：
    Mus musculus (Mouse)
  • 标记方式：
    Non-conjugated

    本页面中的产品，Ccl12 Antibody (CSB-PA09139A0Rb)，的标记方式是Non-conjugated。对于Ccl12 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA09139B0Rb Ccl12 Antibody, HRP conjugated ELISA
    FITC CSB-PA09139C0Rb Ccl12 Antibody, FITC conjugated
    Biotin CSB-PA09139D0Rb Ccl12 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Chemotactic factor that attracts eosinophils, monocytes, and lymphocytes but not neutrophils. Potent monocyte active chemokine that signals through CCR2. Involved in allergic inflammation and the host response to pathogens and may play a pivotal role during early stages of allergic lung inflammation.
  • 基因功能参考文献：
    1. After 100% O2 treatment, genes involved in inflammation (Ccl12), angiogenesis (Igfr1, Stat3), and metabolism (Hk2) were upregulated. PMID: 24458145
    2. Data indicate mRNA upregulation of CCR2 and CCR2 ligands CCL2, CCL7, CCL8, and CCL12 in aortas from DOCA/salt-treated hypertension. PMID: 23033370
    3. The transforming growth factor (TGF)beta type II receptor/MCP-5 axis is an essential crossroad for joint development and endochondral growth. PMID: 22814601
    4. CCL12 proteins were present in the vast majority of tissues investigated. mRNA for these proteins was also expressed in most of these tissues suggesting local production and the ability to respond in situ to inflammatory stimuli. PMID: 20931267
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Intercrine beta (chemokine CC) family
  • 组织特异性：
    Predominantly expressed in the lymph nodes and thymus. Also found in the salivary glands containing lymph nodes, breast, heart, lung, brain, small intestine, kidney and colon.
  • 数据库链接：

    KEGG: mmu:20293

    STRING: 10090.ENSMUSP00000000194

    UniGene: Mm.867