Your Good Partner in Biology Research

CWC27 Antibody

  • 货号:
    CSB-PA032471
  • 规格:
    ¥1100
  • 图片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA032471(CWC27 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他:

产品详情

  • Uniprot No.:
    Q6UX04
  • 基因名:
  • 别名:
    Antigen NY CO10 antibody; Antigen NY-CO-10 antibody; CWC27 antibody; CWC27 spliceosome associated protein homolog (S. cerevisiae) antibody; CWC27 spliceosome associated protein homolog S cerevisiae antibody; CWC27_HUMAN antibody; NY CO 10 antibody; NY-CO-10 antibody; peptidyl prolyl cis trans isomerase CWC27 homolog antibody; Peptidyl prolyl cis trans isomerase SDCCAG10 antibody; Peptidyl-prolyl cis-trans isomerase CWC27 homolog antibody; PPIase CWC27 antibody; PPIase SDCCAG10 antibody; SDCCAG10 antibody; Serologically defined colon cancer antigen 10 antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human,Mouse,Rat
  • 免疫原:
    Synthetic peptide of Human CWC27
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    Non-conjugated
  • 抗体亚型:
    IgG
  • 纯化方式:
    Antigen affinity purification
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA,IHC
  • 推荐稀释比:
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:25-1:100
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    As part of the spliceosome, plays a role in pre-mRNA splicing. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity.
  • 基因功能参考文献:
    1. CWC27 overexpression is associated with Bladder Cancer. PMID: 27206850
    2. By whole-exome sequencing, recessive protein-truncating mutations in CWC27 were found in seven unrelated families that show a range of clinical phenotypes, including retinal degeneration, brachydactyly, craniofacial abnormalities, short stature, and neurologic defects. PMID: 28285769
    3. The crystal structure of a relatively protease-resistant N-terminal fragment of human Cwc27 containing the cyclophilin-type peptidyl-prolyl cis-trans isomerase domain was determined at 2.0 A resolution. PMID: 25478830
  • 相关疾病:
    Retinitis pigmentosa with or without skeletal anomalies (RPSKA)
  • 亚细胞定位:
    Nucleus.
  • 蛋白家族:
    Cyclophilin-type PPIase family
  • 数据库链接:

    HGNC: 10664

    OMIM: 250410

    KEGG: hsa:10283

    STRING: 9606.ENSP00000370460

    UniGene: Hs.371372