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  4. Recombinant Human Peptidyl-prolyl cis-trans isomerase CWC27 homolog (CWC27)

Recombinant Human Peptidyl-prolyl cis-trans isomerase CWC27 homolog (CWC27)

  • 中文名称：
    Recombinant Human Peptidyl-prolyl cis-trans isomerase CWC27 homolog(CWC27),Yeast
  • 货号：
    CSB-YP744267HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human Peptidyl-prolyl cis-trans isomerase CWC27 homolog(CWC27),Yeast
  • 货号：
    CSB-EP744267HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human Peptidyl-prolyl cis-trans isomerase CWC27 homolog(CWC27),Yeast
  • 货号：
    CSB-EP744267HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human Peptidyl-prolyl cis-trans isomerase CWC27 homolog(CWC27),Yeast
  • 货号：
    CSB-BP744267HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human Peptidyl-prolyl cis-trans isomerase CWC27 homolog(CWC27),Yeast
  • 货号：
    CSB-MP744267HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Antigen NY CO10; Antigen NY-CO-10; CWC27; CWC27 spliceosome associated protein homolog (S. cerevisiae); CWC27 spliceosome associated protein homolog S cerevisiae; CWC27_HUMAN; NY CO 10; NY-CO-10; peptidyl prolyl cis trans isomerase CWC27 homolog; Peptidyl prolyl cis trans isomerase SDCCAG10; Peptidyl-prolyl cis-trans isomerase CWC27 homolog; PPIase CWC27; PPIase SDCCAG10; SDCCAG10; Serologically defined colon cancer antigen 10
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-472
  • 氨基酸序列
    SNIYIQEPP TNGKVLLKTT AGDIDIELWS KEAPKACRNF IQLCLEAYYD NTIFHRVVPG FIVQGGDPTG TGSGGESIYG APFKDEFHSR LRFNRRGLVA MANAGSHDNG SQFFFTLGRA DELNNKHTIF GKVTGDTVYN MLRLSEVDID DDERPHNPHK IKSCEVLFNP FDDIIPREIK RLKKEKPEEE VKKLKPKGTK NFSLLSFGEE AEEEEEEVNR VSQSMKGKSK SSHDLLKDDP HLSSVPVVES EKGDAPDLVD DGEDESAEHD EYIDGDEKNL MRERIAKKLK KDTSANVKSA GEGEVEKKSV SRSEELRKEA RQLKRELLAA KQKKVENAAK QAEKRSEEEE APPDGAVAEY RREKQKYEAL RKQQSKKGTS REDQTLALLN QFKSKLTQAI AETPENDIPE TEVEDDEGWM SHVLQFEDKS RKVKDASMQD SDTFEIYDPR NPVNKRRREE SKKLMREKKE RR
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    As part of the spliceosome, plays a role in pre-mRNA splicing. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity.
  • 基因功能参考文献：
    1. CWC27 overexpression is associated with Bladder Cancer. PMID: 27206850
    2. By whole-exome sequencing, recessive protein-truncating mutations in CWC27 were found in seven unrelated families that show a range of clinical phenotypes, including retinal degeneration, brachydactyly, craniofacial abnormalities, short stature, and neurologic defects. PMID: 28285769
    3. The crystal structure of a relatively protease-resistant N-terminal fragment of human Cwc27 containing the cyclophilin-type peptidyl-prolyl cis-trans isomerase domain was determined at 2.0 A resolution. PMID: 25478830
  • 相关疾病：
    Retinitis pigmentosa with or without skeletal anomalies (RPSKA)
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Cyclophilin-type PPIase family
  • 数据库链接：

    HGNC: 10664

    OMIM: 250410

    KEGG: hsa:10283

    STRING: 9606.ENSP00000370460

    UniGene: Hs.371372