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CPN1 Antibody

  • 货号：
    CSB-PA001774
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of Hela cells using CPN cat Polyclonal Antibody
    • Western Blot analysis of HELA cells using CPN cat Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    P15169
  • 基因名：
    CPN1
  • 别名：
    ACBP antibody; Anaphylatoxin inactivator antibody; Arginine carboxypeptidase antibody; Carboxypeptidase N catalytic chain antibody; Carboxypeptidase N polypeptide 1 50 kD antibody; Carboxypeptidase N polypeptide 1 antibody; Carboxypeptidase N small subunit antibody; Carboxypeptidase N subunit 1 antibody; CBPN_HUMAN antibody; CPN antibody; CPN1 antibody; Kininase 1 antibody; Kininase-1 antibody; Kininase1 antibody; Lysine carboxypeptidase antibody; Plasma carboxypeptidase B antibody; SCPN antibody; Serum carboxypeptidase N antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human CPN cat.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation.
  • 基因功能参考文献：
    1. CPN binds to fibrinogen and is present in a fibrin clot prepared from plasma. PMID: 23000409
    2. carboxypeptidase N regulates the biologic activity of SDF-1alpha by reducing the chemokine-specific activity PMID: 15718415
    3. This review summarizes the structure, enzymatic properties and function of this enzyme, including insights gained by the recent elucidation of the crystal structure of the CPN catalytic subunit and structural modeling of the non-catalytic 83 kDa subunit. PMID: 18039526
  • 相关疾病：
    Carboxypeptidase N deficiency (CPND)
  • 亚细胞定位：
    Secreted, extracellular space.
  • 蛋白家族：
    Peptidase M14 family
  • 组织特异性：
    Synthesized in the liver and secreted in plasma.
  • 数据库链接：

    HGNC: 2312

    OMIM: 212070

    KEGG: hsa:1369

    STRING: 9606.ENSP00000359446

    UniGene: Hs.2246