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CNKSR2 Antibody

  • 货号：
    CSB-PA008271
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of 293T cells using CNK2 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q8WXI2
  • 基因名：
    CNKSR2
  • 别名：
    CNKSR2 antibody; CNK2 antibody; KIAA0902 antibody; KSR2Connector enhancer of kinase suppressor of ras 2 antibody; Connector enhancer of KSR 2 antibody; CNK homolog protein 2 antibody; CNK2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human CNK2.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May function as an adapter protein or regulator of Ras signaling pathways.
  • 基因功能参考文献：
    1. High CNKSR2 expression is associated with breast cancer progression. PMID: 29534682
    2. CNKSR2 deletions: a novel cause of X-linked intellectual disability and seizures. PMID: 25754917
    3. This study describes the phenotype of CNKSR2 deficiency and its involvement in systems underlying common neurological PMID: 25223753
    4. CNK2 through interaction with Raf and Rlf may function as a regulator of Ras signaling. PMID: 14597674
    5. CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling. PMID: 18287031

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  • 亚细胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein.
  • 蛋白家族：
    CNKSR family
  • 数据库链接：

    HGNC: 19701

    OMIM: 300724

    KEGG: hsa:22866

    STRING: 9606.ENSP00000368824

    UniGene: Hs.555917