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CNKSR2 Antibody

  • 中文名称：
    CNKSR2兔多克隆抗体
  • 货号：
    CSB-PA005653LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA005653LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA005653LA01HU at dilution of 1:100
    • Immunofluorescence staining of Jurkat cells with CSB-PA005653LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CNKSR2 Polyclonal antibody
  • Uniprot No.：
    Q8WXI2
  • 基因名：
    CNKSR2
  • 别名：
    CNKSR2 antibody; CNK2 antibody; KIAA0902 antibody; KSR2Connector enhancer of kinase suppressor of ras 2 antibody; Connector enhancer of KSR 2 antibody; CNK homolog protein 2 antibody; CNK2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Connector enhancer of kinase suppressor of ras 2 protein (650-800AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CNKSR2 Antibody (CSB-PA005653LA01HU)，的标记方式是Non-conjugated。对于CNKSR2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA005653LB01HU CNKSR2 Antibody, HRP conjugated ELISA
    FITC CSB-PA005653LC01HU CNKSR2 Antibody, FITC conjugated
    Biotin CSB-PA005653LD01HU CNKSR2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May function as an adapter protein or regulator of Ras signaling pathways.
  • 基因功能参考文献：
    1. High CNKSR2 expression is associated with breast cancer progression. PMID: 29534682
    2. CNKSR2 deletions: a novel cause of X-linked intellectual disability and seizures. PMID: 25754917
    3. This study describes the phenotype of CNKSR2 deficiency and its involvement in systems underlying common neurological PMID: 25223753
    4. CNK2 through interaction with Raf and Rlf may function as a regulator of Ras signaling. PMID: 14597674
    5. CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling. PMID: 18287031

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  • 亚细胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein.
  • 蛋白家族：
    CNKSR family
  • 数据库链接：

    HGNC: 19701

    OMIM: 300724

    KEGG: hsa:22866

    STRING: 9606.ENSP00000368824

    UniGene: Hs.555917