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CMBL Antibody

  • 货号：
    CSB-PA846604LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: CMBL antibody at 1µg/ml
      Lane 1: Mouse kidney tissue
      Lane 2: Mouse liver tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 29 kDa
      Observed band size: 29, 25 kDa
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA846604LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA846604LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA846604LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CMBL Polyclonal antibody
  • Uniprot No.：
    Q96DG6
  • 基因名：
    CMBL
  • 别名：
    Carboxymethylenebutenolidase homolog (Pseudomonas) antibody; Carboxymethylenebutenolidase homolog antibody; cmbl antibody; CMBL_HUMAN antibody; FLJ23617 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Carboxymethylenebutenolidase homolog protein (2-245AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CMBL Antibody (CSB-PA846604LA01HU)，的标记方式是Non-conjugated。对于CMBL Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA846604LB01HU CMBL Antibody, HRP conjugated ELISA
    FITC CSB-PA846604LC01HU CMBL Antibody, FITC conjugated
    Biotin CSB-PA846604LD01HU CMBL Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Cysteine hydrolase. Can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine. May also activate beta-lactam antibiotics faropenem medoxomil and lenampicillin.
  • 基因功能参考文献：
    1. By comparing the enzyme kinetics and chemical inhibition properties between the recombinant protein and tissue preparations, CMBL was shown to be the primary olmesartan medoxomil bioactivating enzyme in the liver and intestine. PMID: 20177059
  • 亚细胞定位：
    Cytoplasm, cytosol.
  • 蛋白家族：
    Dienelactone hydrolase family
  • 组织特异性：
    Widely expressed, with highest levels in liver, followed by kidney, small intestine and colon. Present in liver and intestine (at protein level).
  • 数据库链接：

    HGNC: 25090

    OMIM: 613379

    KEGG: hsa:134147

    STRING: 9606.ENSP00000296658

    UniGene: Hs.192586