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CMBL Antibody

  • 中文名称：
    CMBL多克隆抗体
  • 货号：
    CSB-PA005602GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q96DG6
  • 基因名：
    CMBL
  • 别名：
    Carboxymethylenebutenolidase homolog (Pseudomonas) antibody; Carboxymethylenebutenolidase homolog antibody; cmbl antibody; CMBL_HUMAN antibody; FLJ23617 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human CMBL
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Cysteine hydrolase. Can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine. May also activate beta-lactam antibiotics faropenem medoxomil and lenampicillin.
  • 基因功能参考文献：
    1. By comparing the enzyme kinetics and chemical inhibition properties between the recombinant protein and tissue preparations, CMBL was shown to be the primary olmesartan medoxomil bioactivating enzyme in the liver and intestine. PMID: 20177059
  • 亚细胞定位：
    Cytoplasm, cytosol.
  • 蛋白家族：
    Dienelactone hydrolase family
  • 组织特异性：
    Widely expressed, with highest levels in liver, followed by kidney, small intestine and colon. Present in liver and intestine (at protein level).
  • 数据库链接：

    HGNC: 25090

    OMIM: 613379

    KEGG: hsa:134147

    STRING: 9606.ENSP00000296658

    UniGene: Hs.192586