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CENPK Antibody

  • 货号：
    CSB-PA005214ESR2HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: CENPK antibody at 4.17µg/ml
      Lane 1: PC-3 whole cell lysate
      Lane 2: 293T whole cell lysate
      Lane 3: Hela whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 32 kDa
      Observed band size: 32 kDa
    • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA005214ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA005214ESR2HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CENPK Polyclonal antibody
  • Uniprot No.：
    Q9BS16
  • 基因名：
    CENPK
  • 别名：
    CENPK antibody; ICEN37 antibody; FKSG14 antibody; Centromere protein K antibody; CENP-K antibody; Interphase centromere complex protein 37 antibody; Protein AF-5alpha antibody; p33 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Centromere protein K protein (1-269AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Acts in coordination with KNL1 to recruit the NDC80 complex to the outer kinetochore.
  • 相关疾病：
    Chromosomal aberrations involving CENPK are a cause of acute leukemias. Translocation t(5;11)(q12;q23) with KMT2A/MLL1.
  • 亚细胞定位：
    Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
  • 蛋白家族：
    CENP-K/MCM22 family
  • 组织特异性：
    Detected in several fetal organs with highest levels in fetal liver. In adults, it is weakly expressed in lung and placenta.
  • 数据库链接：

    HGNC: 29479

    OMIM: 611502

    KEGG: hsa:64105

    STRING: 9606.ENSP00000242872

    UniGene: Hs.529778