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CEACAM16 Antibody

  • 货号：
    CSB-PA005158LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • IHC image of CSB-PA005158LA01HU diluted at 1:500 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CEACAM16 Polyclonal antibody
  • Uniprot No.：
    Q2WEN9
  • 基因名：
    CEACAM16
  • 别名：
    CEACAM16 antibody; CEAL2Carcinoembryonic antigen-related cell adhesion molecule 16 antibody; Carcinoembryonic antigen-like 2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 16 protein (323-414AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CEACAM16 Antibody (CSB-PA005158LA01HU)，的标记方式是Non-conjugated。对于CEACAM16 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA005158LB01HU CEACAM16 Antibody, HRP conjugated ELISA
    FITC CSB-PA005158LC01HU CEACAM16 Antibody, FITC conjugated
    Biotin CSB-PA005158LD01HU CEACAM16 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:500-1:1000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane.
  • 基因功能参考文献：
    1. Results confirm that CEACAM6 promoted cell proliferation mediated by cyclin D1/CDK4. PMID: 26497080
    2. Data indicate that a heterozygous missense mutation, c.505G>A (p.G169R) in exon 3 of the CEACAM16 gene (carcinoembryonic antigen-related cell adhesion molecule 16) was identified in autosomal dominant nonsyndromic hearing loss family. PMID: 25589040
    3. CEACAM16 can probably form higher order structures with other tectorial membrane proteins such as alpha-tectorin and beta-tectorin and influences the physical properties of the tectorial membrane PMID: 22544735
    4. data identify CEACAM16 as an alpha-tectorin-interacting protein that concentrates at the point of attachment of the TM to the stereocilia and, when mutated, results in ADNSHL at the DFNA4 locus PMID: 21368133
  • 相关疾病：
    Deafness, autosomal dominant, 4B (DFNA4B)
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Immunoglobulin superfamily, CEA family
  • 数据库链接：

    HGNC: 31948

    OMIM: 614591

    KEGG: hsa:388551

    STRING: 9606.ENSP00000385576

    UniGene: Hs.456381