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CDH15 Antibody

  • 货号：
    CSB-PA005040LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Rat heart tissue
      All lanes: CDH15 antibody at 3.2μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 89 kDa
      Observed band size: 89 kDa
    • Immunofluorescence staining of HepG2 cells with CSB-PA005040LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CDH15 Polyclonal antibody
  • Uniprot No.：
    P55291
  • 基因名：
    CDH15
  • 别名：
    CDH15; CDH14; CDH3; Cadherin-15; Cadherin-14; Muscle cadherin; M-cadherin
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Rat
  • 免疫原：
    Recombinant Human Cadherin-15 protein (639-766AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CDH15 Antibody (CSB-PA005040LA01HU)，的标记方式是Non-conjugated。对于CDH15 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA005040LB01HU CDH15 Antibody, HRP conjugated ELISA
    FITC CSB-PA005040LC01HU CDH15 Antibody, FITC conjugated
    Biotin CSB-PA005040LD01HU CDH15 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation.
  • 基因功能参考文献：
    1. The cell adhesion molecule M-cadherin is not essential for muscle development and regeneration. PMID: 12052883
    2. Alterations in CDH15 in patients with mild to severe intellectual disability are reported. PMID: 19012874
  • 相关疾病：
    Mental retardation, autosomal dominant 3 (MRD3)
  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 组织特异性：
    Expressed in the brain and cerebellum.
  • 数据库链接：

    HGNC: 1754

    OMIM: 114019

    KEGG: hsa:1013

    STRING: 9606.ENSP00000289746

    UniGene: Hs.148090