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CDH15 Antibody

  • 货号：
    CSB-PA003206
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of HepG2 cells using M-cadherin Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    P55291
  • 基因名：
    CDH15
  • 别名：
    CDH15; CDH14; CDH3; Cadherin-15; Cadherin-14; Muscle cadherin; M-cadherin
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human M-cadherin.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation.
  • 基因功能参考文献：
    1. The cell adhesion molecule M-cadherin is not essential for muscle development and regeneration. PMID: 12052883
    2. Alterations in CDH15 in patients with mild to severe intellectual disability are reported. PMID: 19012874
  • 相关疾病：
    Mental retardation, autosomal dominant 3 (MRD3)
  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 组织特异性：
    Expressed in the brain and cerebellum.
  • 数据库链接：

    HGNC: 1754

    OMIM: 114019

    KEGG: hsa:1013

    STRING: 9606.ENSP00000289746

    UniGene: Hs.148090