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CCDC170 Antibody

  • 货号：
    CSB-PA815585LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: HepG2 whole cell lysate, PC-3 whole cell lysate
      All lanes: CCDC170 antibody at 5µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 83 kDa
      Observed band size: 83 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CCDC170 Polyclonal antibody
  • Uniprot No.：
    Q8IYT3
  • 基因名：
    CCDC170
  • 别名：
    bA282P11.1 antibody; CC170_HUMAN antibody; CCDC170 antibody; Chromosome 6 open reading frame 97 antibody; Coiled coil domain containing protein C6orf97 antibody; Coiled-coil domain-containing protein 170 antibody; FLJ23305 antibody; Hypothetical protein LOC80129 antibody; LOC80129 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Coiled-coil domain-containing protein 170 protein (574-651AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CCDC170 Antibody (CSB-PA815585LA01HU)，的标记方式是Non-conjugated。对于CCDC170 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA815585LB01HU CCDC170 Antibody, HRP conjugated ELISA
    FITC CSB-PA815585LC01HU CCDC170 Antibody, FITC conjugated
    Biotin CSB-PA815585LD01HU CCDC170 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a role in Golgi-associated microtubules organization and stabilization.
  • 基因功能参考文献：
    1. Findings demonstrate that CCDC170 plays an essential role in Golgi-associated microtubules organization and stabilization, and implicate a mechanism for how perturbations in the CCDC170 gene may contribute to the hallmark changes in cell polarity and motility seen in breast cancer. PMID: 28687497
    2. Data suggest that rs2046210 SNPs located in the region of C6ORF97 (CCDC170)-estrogen receptor alpha (ESR1) might have substantial roles not only in carcinogenesis but also in progression toward a more aggressive phenotype in breast cancer patients. PMID: 25370037
    3. Our findings suggest that ESR1 and C6orf97 gene polymorphism is associated with fracture and vertebral fracture risk in Chinese postmenopausal women. PMID: 24481879
    4. ESR1-CCDC170 rearrangements are found in an aggressive subset of estrogen receptor-positive breast cancers PMID: 25099679
    5. Variation in rs3757318 of C6orf97 is associated with breast cancer risk. PMID: 25338983
    6. SNPs associated with breast cancer differ for Asian, European, and African ancestry groups PMID: 20661439

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  • 亚细胞定位：
    Golgi apparatus.
  • 数据库链接：

    HGNC: 21177

    KEGG: hsa:80129

    STRING: 9606.ENSP00000239374

    UniGene: Hs.660044