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Vegfa

VEGFA,即血管内皮生长因子A(Vascular Endothelial Growth Factor A),是一种关键的血管生成调节因子,由多种细胞类型分泌,包括内皮细胞、巨噬细胞和肿瘤细胞。其作用机制主要通过与其特异性酪氨酸激酶受体VEGFR1和VEGFR2结合,特别是VEGFR2,激活下游的信号传导途径,如JAK-STAT、MAPK和PI3K等,从而促进内皮细胞的增殖、迁移、存活和血管通透性的增加。VEGFA在生理性血管生成中的核心作用,如在胚胎发育、组织修复和女性生殖系统等过程中至关重要。此外,VEGFA在病理性血管生成中也起着关键作用,特别是在肿瘤血管生成、某些炎症性疾病和年龄相关性眼病中,因此是多种疾病治疗的重要靶点。

热销产品

Recombinant Human Vascular endothelial growth factor A (VEGFA) (CSB-YP025833HU)

验证数据

CSB-YP025833HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Vegfa Antibody (CSB-PA08249A0Rb)

验证数据

CSB-PA08249A0Rb

Western Blot
Positive WB detected in: Rat liver tissue
All lanes: Vegfa antibody at 4.8µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 26, 23, 21, 18 kDa
Observed band size: 26 kDa

CSB-PA08249A0Rb

Immunohistochemistry of paraffin-embedded mouse lung tissue using CSB-PA08249A0Rb at dilution of 1:100

Human Vascular Endothelial cell Growth Factor(VEGF) ELISA KIT (CSB-E11718h)

验证数据

CSB-E11718h 标准曲线

货号:CSB-E11718h

规格:96T/48T

灵敏度:25.297 pg/mL

检测范围:31.25 pg/mL-2000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Vegfa Antibodies

Vegfa for Pig

Vegfa for Homo sapiens (Human)

Vegfa for Rattus norvegicus (Rat)

Vegfa Proteins

Vegfa Proteins for Gallus gallus (Chicken)

Vegfa Proteins for Rattus norvegicus (Rat)

Vegfa Proteins for Homo sapiens (Human)

Vegfa Proteins for Bos taurus (Bovine)

Vegfa Proteins for Cavia porcellus (Guinea pig)

Vegfa Proteins for Sus scrofa (Pig)

Vegfa Proteins for Ovis aries (Sheep)

Vegfa Proteins for Coturnix coturnix japonica (Japanese quail) (Coturnix japonica)

Vegfa Proteins for Mesocricetus auratus (Golden hamster)

Vegfa Proteins for Equus caballus (Horse)

Vegfa Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

Vegfa ELISA Kit

Vegfa ELISA Kit for Bos taurus (Bovine)

Vegfa ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)

Vegfa ELISA Kit for Homo sapiens (Human)

Vegfa ELISA Kit for Mus musculus (Mouse)

Vegfa ELISA Kit for Sus scrofa (Pig)

Vegfa ELISA Kit for Rattus norvegicus (Rat)