TNFSF9
TNFSF9是一种膜结合蛋白,它包括一个细胞外胞糖化的结构域,一个跨膜域以及一个细胞内结构域。细胞外结构域是与其受体4-1BB(CD137)相互作用的关键部分。TNFSF9的主要功能是调节免疫细胞的活性,特别是T细胞的活性。当TNFSF9与其受体4-1BB结合时,它可以激活T细胞,并增强它们的生存、增殖和效应功能。TNFSF9的研究已经引起了在免疫治疗领域的广泛兴趣。4-1BB受体的激活可以增强T细胞的抗肿瘤免疫反应,因此研究人员正在开发TNFSF9相关的治疗方法,包括4-1BB激动剂。这些治疗方法的目标是增强免疫系统对癌细胞的攻击性,提高免疫治疗的疗效。此外,TNFSF9的研究还有助于深入了解免疫调节的机制,可能为其他免疫性和炎症性疾病的治疗提供新的思路。
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验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized TNFSF9 at 2 μg/ml can bind TNFRSF9(CSB-MP023984HU1), the EC50 is 2.671-3.702 ng/mL.
TNFSF9 Antibodies
TNFSF9 for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA08047A0Rb | TNFSF9 Antibody | Human | ELISA, IHC, IF |
CSB-PA08047B0Rb | TNFSF9 Antibody, HRP conjugated | Human | ELISA |
CSB-PA203832 | TNFSF9 Antibody | Human | ELISA,WB,IF |
CSB-PA001424 | TNFSF9 Antibody | Human | IF, ELISA |
TNFSF9 Proteins
TNFSF9 Proteins for Mus musculus (Mouse)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP023997MO1 CSB-EP023997MO1 CSB-BP023997MO1 CSB-MP023997MO1 CSB-EP023997MO1-B |
Recombinant Mouse Tumor necrosis factor ligand superfamily member 9 (Tnfsf9), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF023997MO | Recombinant Mouse Tumor necrosis factor ligand superfamily member 9 (Tnfsf9) | in vitro E.coli expression system |
TNFSF9 Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP023997HU CSB-EP023997HU CSB-BP023997HU CSB-MP023997HU CSB-EP023997HU-B |
Recombinant Human Tumor necrosis factor ligand superfamily member 9 (TNFSF9), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-RP080474h | Recombinant Human Tumor necrosis factor ligand superfamily member 9 protein (TNFSF9), partial | E.coli |
CSB-AP001961HU | Recombinant Human Tumor necrosis factor ligand superfamily member 9 (TNFSF9), partial (Active) | E.Coli |
CSB-CF023997HU(A4) | Recombinant Human Tumor necrosis factor ligand superfamily member 9 (TNFSF9) | in vitro E.coli expression system |
CSB-MP023997HU1 | Recombinant Human Tumor necrosis factor ligand superfamily member 9 (TNFSF9), partial (Active) | Mammalian cell |
TNFSF9 ELISA Kit
TNFSF9 ELISA Kit for Homo sapiens (Human)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-EL023997HU | Human Tumor necrosis factor ligand superfamily member 9(TNFSF9) ELISA kit | serum, plasma, tissue homogenates | 4.7 pg/mL |
TNFSF9 ELISA Kit for Mus musculus (Mouse)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-EL023997MO | Mouse Tumor necrosis factor ligand superfamily member 9(TNFSF9) ELISA kit | serum, plasma, tissue homogenates | 5.8 pg/mL |