Nampt

NAMPT，即烟酰胺磷酸核糖基转移酶，别名PBEF、Visfatin、前B细胞集落增强因子等。它是一种由NAMPT基因编码的多功能蛋白，主要在多种组织中表达，如棕色脂肪组织、肝脏、肾脏等，尤其在脂肪组织中表达量较高。NAMPT的作用机制主要是催化烟酰胺(NAM)和5'-磷酸核糖焦磷酸(PRPP)合成烟酰胺单核苷酸(NMN)，这是NAD+合成补救途径的第一步和限速步骤。NAMPT在生物学上的意义非常广泛，它不仅在细胞内NAD+的合成和能量代谢中发挥关键作用，还以分泌型eNAMPT的形式参与多种生理和病理过程的调节。eNAMPT具有细胞因子样活性，能够促进炎症和血管生成，与肿瘤的发生、发展以及转移密切相关。此外，NAMPT的表达水平在代谢性疾病、神经退行性疾病、衰老和癌症等多种年龄相关性疾病中发生变化，提示其在这些疾病中可能发挥重要作用。因此，NAMPT是药物开发和疾病治疗中的一个潜在靶点，针对NAMPT的激活剂和抑制剂正在被研究用于治疗相关疾病。

热销产品

Recombinant Mouse Nicotinamide phosphoribosyltransferase (Nampt) (CSB-YP015422MOb0)

验证数据

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

NAMPT Antibody (CSB-PA015422ESR2HU)

验证数据

Western blot
All lanes: Nicotinamide phosphoribosyltransferase antibody at 4μg/ml
Lane 1: Mouse heart tissue
Lane 2: Mouse liver tissue
Lane 3: Mouse skeletal muscle tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 56 kDa
Observed band size: 56 kDa

Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA015422ESR2HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA015422ESR2HU at dilution of 1:100

Nampt Antibody

Nampt Protein

Nampt ELISA Kit

Nampt Antibodies

Nampt for Homo sapiens (Human)

产品货号	产品名称	种属反应性	应用类型
CSB-PA015422GA01HU	NAMPT Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA015422ESR1HU	NAMPT Antibody	Human	ELISA, IHC, IP
CSB-PA015422ESR2HU	NAMPT Antibody	Human, Mouse	ELISA, WB, IHC
CSB-PA215740	NAMPT Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA200625	NAMPT Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA015422EA01HU	NAMPT Antibody	Human	ELISA, WB, IHC, IF
CSB-PA015422EB01HU	NAMPT Antibody, HRP conjugated	Human	ELISA
CSB-PA015422EC01HU	NAMPT Antibody, FITC conjugated	Human
CSB-PA015422ED01HU	NAMPT Antibody, Biotin conjugated	Human	ELISA

Nampt for Rattus norvegicus (Rat)

产品货号	产品名称	种属反应性	应用类型
CSB-PA015422LA01RA	Nampt Antibody	Rat, Human	ELISA, WB
CSB-PA015422LB01RA	Nampt Antibody, HRP conjugated	Rat	ELISA
CSB-PA015422LC01RA	Nampt Antibody, FITC conjugated	Rat
CSB-PA015422LD01RA	Nampt Antibody, Biotin conjugated	Rat	ELISA

Nampt Proteins

Nampt Proteins for Homo sapiens (Human)

产品货号	产品名称	来源
CSB-YP015422HU CSB-EP015422HU CSB-BP015422HU CSB-MP015422HU CSB-EP015422HU-B	Recombinant Human Nicotinamide phosphoribosyltransferase (NAMPT)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Nampt Proteins for Sus scrofa (Pig)

产品货号	产品名称	来源
CSB-YP015422PI CSB-EP015422PI CSB-BP015422PI CSB-MP015422PI CSB-EP015422PI-B	Recombinant Pig Nicotinamide phosphoribosyltransferase (NAMPT)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Nampt Proteins for Rattus norvegicus (Rat)

产品货号	产品名称	来源
CSB-YP015422RA CSB-EP015422RA CSB-BP015422RA CSB-MP015422RA CSB-EP015422RA-B	Recombinant Rat Nicotinamide phosphoribosyltransferase (Nampt)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Nampt Proteins for Mus musculus (Mouse)

产品货号	产品名称	来源
CSB-YP015422MO CSB-BP015422MO CSB-MP015422MO CSB-EP015422MO-B	Recombinant Mouse Nicotinamide phosphoribosyltransferase (Nampt)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP015422MO(M1)	Recombinant Mouse Nicotinamide phosphoribosyltransferase (Nampt) (C39S)	E.coli
CSB-EP015422MO	Recombinant Mouse Nicotinamide phosphoribosyltransferase (Nampt)	E.coli
CSB-EP015422MOe1	Recombinant Mouse Nicotinamide phosphoribosyltransferase (Nampt)	E.coli
CSB-YP015422MOb0	Recombinant Mouse Nicotinamide phosphoribosyltransferase (Nampt)	Yeast