MGRN1
E3 ubiquitin-protein ligase MGRN1 is a protein in humans that is encoded by MGRN1 gene. E3 ubiquitin-protein ligase. Mediates monoubiquitination at multiple sites of TSG101 in the presence of UBE2D1, but not of UBE2G1, nor UBE2H. Plays a role in the regulation of endosome-to-lysosome trafficking. Impairs MC1R- and MC4R-signaling by competing with GNAS-binding to MCRs and inhibiting agonist-induced cAMP production. Does not inhibit ADRB2-signaling. Does not promote MC1R ubiquitination.
MGRN1 Antibodies
MGRN1 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA013790GA01HU | MGRN1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
MGRN1 Proteins
MGRN1 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP013790HU CSB-EP013790HU CSB-BP013790HU CSB-MP013790HU CSB-EP013790HU-B |
Recombinant Human E3 ubiquitin-protein ligase MGRN1 (MGRN1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MGRN1 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP736462RA CSB-EP736462RA CSB-BP736462RA CSB-MP736462RA CSB-EP736462RA-B |
Recombinant Rat E3 ubiquitin-protein ligase MGRN1 (Mgrn1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MGRN1 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP801862DIL CSB-EP801862DIL CSB-BP801862DIL CSB-MP801862DIL CSB-EP801862DIL-B |
Recombinant Danio rerio Probable E3 ubiquitin-protein ligase MGRN1 (mgrn1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MGRN1 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP880460MO CSB-EP880460MO CSB-BP880460MO CSB-MP880460MO CSB-EP880460MO-B |
Recombinant Mouse E3 ubiquitin-protein ligase MGRN1 (Mgrn1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
