KDR
KDR,即Kinase Domain-containing Receptor,也被称为血管内皮生长因子受体2。KDR是一种跨膜受体酪氨酸激酶,主要在血管内皮细胞表达,参与调控血管生成和维护血管的完整性。其作用机制涉及与VEGF家族成员如VEGFA、VEGFC和VEGFD的结合,激活后引发受体二聚化和自身酪氨酸激酶活性,进而触发下游信号通路,如PI3K-Akt、Ras-Raf-MEK-ERK等,这些通路促进内皮细胞的增殖、迁移和血管通透性的增加。KDR在胚胎发育、组织修复、伤口愈合中发挥关键作用,是正常生理功能中必不可少的。同时,KDR的功能在多种病理状态下也至关重要,尤其是在肿瘤血管生成中,其过度激活与多种肿瘤的进展、转移密切相关,使其成为癌症治疗的重要靶点。此外,KDR还在某些心血管疾病中发挥作用,是研究和治疗相关疾病的潜在靶点。
KDR Antibodies
KDR for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA07279A0Rb | KDR Antibody | Human | ELISA, IHC |
CSB-PA07279B0Rb | KDR Antibody, HRP conjugated | Human | ELISA |
CSB-PA07279C0Rb | KDR Antibody, FITC conjugated | Human | |
CSB-PA07279D0Rb | KDR Antibody, Biotin conjugated | Human | ELISA |
CSB-PA012145GA01HU | KDR Antibody | Human,Mouse,Rat | ELISA,WB |
CSB-PA898056 | Phospho-KDR (Tyr1175) Antibody | Human,Mouse,Rat | ELISA,IHC,IF |
CSB-PA917275 | Phospho-KDR (Tyr1214) Antibody | Human,Mouse | ELISA,WB,IHC,IF |
CSB-PA200726 | Phospho-KDR (Tyr951) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA905984 | KDR (Ab-1175) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA274392 | KDR (Ab-1214) Antibody | Human,Mouse | ELISA,WB,IHC,IF |
CSB-PA920878 | KDR (Ab-951) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA444815 | Phospho-KDR (Tyr1059) Antibody | Human,Mouse | ELISA,WB |
CSB-PA070091 | KDR (Ab-1059) Antibody | Human,Mouse | ELISA,WB |
CSB-PA000527 | Phospho-KDR (Y1175) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA000528 | Phospho-KDR (Y1214) Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA002542 | KDR Antibody | Human,Mouse | WB, IHC, IF, ELISA |
CSB-PA002543 | KDR Antibody | Human,Mouse,Rat | WB, ELISA |
CSB-PA009633 | Phospho-KDR (Y951) Antibody | Human,Mouse | WB, IHC, IF, ELISA |
CSB-PA009634 | Phospho-KDR (Y1059) Antibody | Human,Mouse,Rat | WB, ELISA |
CSB-PA009638 | KDR Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA009642 | KDR Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA490567 | KDR Antibody | Human,Mouse,Rat | IHC,ELISA |
KDR Proteins
KDR Proteins for Mus musculus (Mouse)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP012145MO CSB-EP012145MO CSB-BP012145MO CSB-MP012145MO CSB-EP012145MO-B |
Recombinant Mouse Vascular endothelial growth factor receptor 2 (Kdr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KDR Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP012145HU CSB-BP012145HU CSB-MP012145HU CSB-EP012145HU-B |
Recombinant Human Vascular endothelial growth factor receptor 2 (KDR), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP012145HU | Recombinant Human Vascular endothelial growth factor receptor 2 (KDR), partial | E.coli |
KDR Proteins for Rattus norvegicus (Rat)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP012145RA CSB-EP012145RA CSB-BP012145RA CSB-MP012145RA CSB-EP012145RA-B |
Recombinant Rat Vascular endothelial growth factor receptor 2 (Kdr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KDR Proteins for Coturnix coturnix japonica (Japanese quail) (Coturnix japonica)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP346773DXJ CSB-EP346773DXJ CSB-BP346773DXJ CSB-MP346773DXJ CSB-EP346773DXJ-B |
Recombinant Coturnix coturnix japonica Vascular endothelial growth factor receptor 2 (KDR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KDR Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP708034DIL CSB-EP708034DIL CSB-BP708034DIL CSB-MP708034DIL CSB-EP708034DIL-B |
Recombinant Danio rerio Vascular endothelial growth factor receptor 2 (kdr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KDR ELISA Kit
KDR ELISA Kit for Homo sapiens (Human)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-E04763h | Human Vascular endothelial cell growth factor receptor 2,VEGFR-2/Flk-1 ELISA kit | serum, plasma, tissue homogenates | 0.098 ng/mL |
KDR ELISA Kit for Mus musculus (Mouse)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-E04764m | Mouse Vascular endothelial cell growth factor receptor 2,VEGFR-2/Flk-1 ELISA kit | serum, plasma | 1.95 pg/mL |
KDR ELISA Kit for Rattus norvegicus (Rat)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-E07348r | Rat Vascular endothelial cell growth factor receptor 2,VEGFR-2/Flk-1 ELISA kit | serum, plasma, tissue homogenates | 0.39 ng/mL |