Il5
IL5，即白介素5，它主要由活化的T细胞产生，也可由某些人T细胞白血病细胞系、EB病毒转化的B细胞以及嗜酸性粒细胞产生。IL5的作用机制涉及到与特定的细胞表面受体结合，其受体由IL-5Rα链和信号传导亚基βc组成，形成高亲和受体。IL5通过与IL-5Rα的低亲和结合，再紧密结合βc二聚体，激活下游的信号传导途径，如JAK/STAT通路，进而促进嗜酸性粒细胞的分化、成熟、活化、迁移和存活。IL5在生物学上的意义主要体现在其对嗜酸性粒细胞相关生物学过程的调控作用。它在寄生虫感染和过敏性疾病的发病机制中起到关键作用，特别是在嗜酸性粒细胞增多症和某些变态反应性疾病中，IL5的水平会增高。IL5通过促进嗜酸性粒细胞的增殖和活化，增强其杀伤肿瘤细胞和病原体的能力，同时在粘膜免疫中也发挥重要作用。此外，IL5还参与调节B细胞的分化和抗体的产生，尤其是在IgA的合成中具有协同作用。因此，IL5是免疫应答中的一个重要细胞因子，对维持免疫平衡和防御机制具有重要影响。
热销产品
Recombinant Human Interleukin-5 (IL5) (CSB-MP011662HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
验证数据
Western Blot analysis of HuvEc cells using IL-5 Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human breast carcinoma tissue using CSB-PA003033 at dilution of 1:100
Rat Interleukin 5,IL-5 ELISA KIT (CSB-E07435r)
验证数据
货号：CSB-E07435r
规格：96T/48T
灵敏度：3.9 pg/mL
检测范围：15.6 pg/mL-1000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
Il5 Antibodies
Il5 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA003033 | IL5 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
Il5 Proteins
Il5 Proteins for Macaca mulatta (Rhesus macaque)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011662MOW CSB-EP011662MOW CSB-BP011662MOW CSB-MP011662MOW CSB-EP011662MOW-B |
Recombinant Macaca mulatta (Rhesus macaque) Interleukin-5 (IL5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP003091MOW | Recombinant Rhesus Macaque Interleukin-5 protein (IL5) (Active) | E.Coli |
Il5 Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011662BO CSB-EP011662BO CSB-BP011662BO CSB-MP011662BO CSB-EP011662BO-B |
Recombinant Bovine Interleukin-5 (IL5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il5 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011662MO CSB-EP011662MO CSB-BP011662MO CSB-MP011662MO CSB-EP011662MO-B |
Recombinant Mouse Interleukin-5 (Il5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP003311MO | Recombinant Mouse Interleukin-5 protein (Il5) | E.Coli |
Il5 Proteins for Equus caballus (Horse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011662HO CSB-EP011662HO CSB-BP011662HO CSB-MP011662HO CSB-EP011662HO-B |
Recombinant Horse Interleukin-5 (IL5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il5 Proteins for Cavia porcellus (Guinea pig)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011662GU CSB-EP011662GU CSB-BP011662GU CSB-MP011662GU CSB-EP011662GU-B |
Recombinant Guinea pig Interleukin-5 (IL5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il5 Proteins for Felis catus (Cat) (Felis silvestris catus)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011662CA CSB-EP011662CA CSB-BP011662CA CSB-MP011662CA CSB-EP011662CA-B |
Recombinant Cat Interleukin-5 (IL5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il5 Proteins for Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011662DRI CSB-EP011662DRI CSB-BP011662DRI CSB-MP011662DRI CSB-EP011662DRI-B |
Recombinant Cercocebus atys Interleukin-5 (IL5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il5 Proteins for Ovis aries (Sheep)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP637909SH CSB-EP637909SH CSB-BP637909SH CSB-MP637909SH CSB-EP637909SH-B |
Recombinant Sheep Interleukin-5 (IL5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il5 Proteins for Meriones unguiculatus (Mongolian jird) (Mongolian gerbil)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP733829MRA CSB-EP733829MRA CSB-BP733829MRA CSB-MP733829MRA CSB-EP733829MRA-B |
Recombinant Meriones unguiculatus Interleukin-5 (IL5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il5 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP842539DO CSB-EP842539DO CSB-BP842539DO CSB-MP842539DO CSB-EP842539DO-B |
Recombinant Dog Interleukin-5 (IL5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il5 Proteins for Sigmodon hispidus (Hispid cotton rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP861706SZK CSB-EP861706SZK CSB-BP861706SZK CSB-MP861706SZK CSB-EP861706SZK-B |
Recombinant Sigmodon hispidus Interleukin-5 (IL5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il5 Proteins for Sus scrofa (Pig)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP863067PI | Recombinant Pig Interleukin-5 (IL5) | Yeast |
| CSB-EP863067PI | Recombinant Pig Interleukin-5 (IL5) | E.coli |
| CSB-BP863067PI CSB-MP863067PI CSB-EP863067PI-B |
Recombinant Pig Interleukin-5 (IL5) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il5 Proteins for Macropus eugenii (Tammar wallaby)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP895944MPE CSB-EP895944MPE CSB-BP895944MPE CSB-MP895944MPE CSB-EP895944MPE-B |
Recombinant Macropus eugenii Interleukin-5 (IL5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il5 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-AP001721HU | Recombinant Human Interleukin-5 protein (IL5) | E.Coli |
| CSB-EP011662HU CSB-BP011662HU CSB-EP011662HU-B |
Recombinant Human Interleukin-5 (IL5) | E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-YP011662HU | Recombinant Human Interleukin-5 (IL5) | Yeast |
| CSB-AP004291HU | Recombinant Human Interleukin-5 (IL5) (Active) | Mammalian cell |
| CSB-MP011662HU | Recombinant Human Interleukin-5 (IL5) | Mammalian cell |
| CSB-MP011662HUa0 | Recombinant Human Interleukin-5 (IL5) | Mammalian cell |
Il5 ELISA Kit
Il5 ELISA Kit for Guinea Sus scrofa (Pig)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E12064Gp | Guinea pig interleukin 5,IL-5 ELISA Kit | serum, plasma, tissue homogenates | 7.81 pg/mL |
Il5 ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E04636h | Human Interleukin 5,IL-5 ELISA KIT | serum, plasma, tissue homogenates | 0.97 pg/ml |
Il5 ELISA Kit for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E04637m | Mouse Interleukin 5,IL-5 ELISA KIT | serum, plasma, tissue homogenates | 3.9 pg/ml |
Il5 ELISA Kit for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E07435r | Rat Interleukin 5,IL-5 ELISA KIT | serum, plasma, cell culture supernates, tissue homogenates | 3.9 pg/mL |
