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Egr1

Early growth response protein 1 is a protein in humans that is encoded by EGR1 gene. Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes (By similarity). Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Activates expression of p53/TP53 and TGFB1, and thereby helps prevent tumor formation.

Egr1 Antibodies

Egr1 for Homo sapiens (Human)

Egr1 Proteins

Egr1 Proteins for Homo sapiens (Human)

Egr1 Proteins for Mus musculus (Mouse)

Egr1 Proteins for Rattus norvegicus (Rat)

Egr1 Proteins for Gallus gallus (Chicken)

Egr1 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

Egr1 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

Egr1 Proteins for Coturnix coturnix japonica (Japanese quail) (Coturnix japonica)

Egr1 Proteins for Serinus canaria (Island canary) (Fringilla canaria)

Egr1 Proteins for Taeniopygia guttata (Zebra finch) (Poephila guttata)

Egr1 Proteins for Bos taurus (Bovine)