ENPP3
外核苷酸焦磷酸酶/磷酸二酯酶家族成员3是一种由ENPP3基因编码的酶。Hiroaki在2013年的实验中对N2a细胞进行研究,纯化了存在于GnT-IX中的一种内源性抑制因子,发现其与外核苷酸焦磷酸酶/磷酸二酯酶3 (ENPP3)相同,这一结果通过质谱分析以及培养细胞中ENPP3的敲除和过表达得到了证明。动力学分析显示,ENPP3导致的GnT-IX抑制机制是ENPP3介导的核苷酸糖供体底物UDP-GlcNAc水解,从而生成UMP(一种强效竞争性GnT-IX抑制剂)。实际上,当对细胞内的ENPP3敲除,细胞内核苷酸糖水平显著升高,并显示出细胞总糖基化特征的变化。除了糖基转移酶的伴侣或其他已知调节剂外,ENPP3介导的核苷酸糖水解将对糖基转移酶活性产生也会产生广泛和显著的影响,并负责改变细胞总糖基化特征和调节细胞功能。
热销产品
验证数据
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(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis ENPP3 at 2 μg/ml can bind Anti-ENPP3 recombinant antibody (CSB-RA007681MA1HU), the EC50 is 3.313-4.724 ng/mL.
验证数据
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(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ENPP3 at 2 μg/ml can bind anti-ENPP3 recombinant antibody (CSB-RA007681MA1HU), the EC50 is 2.151-2.492 ng/mL.
● ENPP3 Recombinant Monoclonal Antibody CSB-RA007681MA1HU
验证数据
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The Binding Activity of Macaca fascicularis ENPP3 with Anti-ENPP3 recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis ENPP3 (CSB-MP4278MOV) at 2 μg/mL can bind Anti-ENPP3 recombinant antibody, the EC50 is 3.313-4.724 ng/mL.
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The Binding Activity of Huamn ENPP3 with Anti- ENPP3 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ENPP3(CSB-MP007681HU) at 2 μg/mL can bind Anti-ENPP3 recombinant antibody, the EC50 is 2.151-2.492 ng/mL
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Untransfected HEK293T cells (green line) and transfected Human ENPP3 HEK293T stable cells (red line) were stained with anti-ENPP3 recombinant antibody (2µg/1*106cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
● HEK293T/Human ENPP3 Stable Cell Line CSB-SC007681HU
验证数据
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Untransfected HEK293T cells (green line) and transfected Human ENPP3 HEK293T Stable cells (red line) were stained with anti-ENPP3 antibody (2µg/1*106cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
ENPP3 Antibodies
ENPP3 for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA005288 | ENPP3 Antibody | Human,Mouse,Rat | WB, ELISA |
CSB-PA575380 | ENPP3 Antibody | Human,Mouse,Rat | ELISA,IHC |
CSB-PA448237 | ENPP3 Antibody | Human,Mouse,Rat | ELISA,IHC |
ENPP3 Proteins
ENPP3 Proteins for Rattus norvegicus (Rat)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP007681RA CSB-EP007681RA CSB-BP007681RA CSB-MP007681RA CSB-EP007681RA-B |
Recombinant Rat Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (Enpp3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ENPP3 Proteins for Bos taurus (Bovine)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP007681BO CSB-EP007681BO CSB-BP007681BO CSB-MP007681BO CSB-EP007681BO-B |
Recombinant Bovine Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (ENPP3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ENPP3 Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP007681HU CSB-EP007681HU CSB-BP007681HU CSB-EP007681HU-B |
Recombinant Human Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (ENPP3), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
ENPP3 Proteins for Pongo abelii (Sumatran orangutan)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP719125PYX CSB-EP719125PYX CSB-BP719125PYX CSB-MP719125PYX CSB-EP719125PYX-B |
Recombinant Pongo abelii Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (ENPP3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ENPP3 Proteins for Mus musculus (Mouse)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP735351MO CSB-EP735351MO CSB-BP735351MO CSB-MP735351MO CSB-EP735351MO-B |
Recombinant Mouse Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (Enpp3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ENPP3 ELISA Kit
ENPP3 ELISA Kit for Homo sapiens (Human)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-EL007681HU | Human Ectonucleotide pyrophosphatase/phosphodiesterase family member 3(ENPP3) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 0.039 ng/mL |