Cd86

CD86，即分化簇86，别名B7-2、CD28配体2。它是一种主要表达在抗原呈递细胞上的共刺激分子，属于免疫球蛋白超家族成员。CD86由人体细胞自身的基因编码，其作用机制主要是通过与T细胞表面的CD28或CTLA-4（细胞毒性T淋巴细胞相关蛋白4）相互作用，提供共刺激信号，从而促进T细胞的激活、增殖和分化。在M1型巨噬细胞（促炎性巨噬细胞）中，CD86的表达水平通常较高，可以与T细胞的CD28结合，促进T细胞的活化，加强免疫应答和炎症反应。在生物学意义上，CD86在免疫应答中扮演着重要角色。它参与了T细胞的激活过程，对维持免疫平衡和调节免疫反应的强度至关重要。此外，CD86的表达也与某些疾病的发生发展有关，例如在自身免疫疾病和慢性炎症性疾病中，CD86的异常表达可能导致免疫反应的失调。因此，针对CD86的治疗策略正在被研究，以期用于治疗相关疾病。

热销产品

CD86 Recombinant Monoclonal Antibody (CSB-RA004965A0HU)

验证数据

Western Blot
Positive WB detected in Hela whole cell lysate
All lanes CD86 antibody at 0.55μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 70 KDa
Observed band size: 70 KDa

Cd86 Antibody

Cd86 Protein

Cd86 ELISA Kit

Cd86 Antibodies

Cd86 for Homo sapiens (Human)

产品货号	产品名称	种属反应性	应用类型
CSB-PA004965GA01HU	CD86 Antibody	Human, Rat	ELISA, WB, IHC, IF, FC
CSB-PA004965EA01HU	CD86 Antibody	Human	ELISA
CSB-RA004965A0HU	CD86 Recombinant Monoclonal Antibody	Human	ELISA, WB

Cd86 Proteins

Cd86 Proteins for Mus musculus (Mouse)

产品货号	产品名称	来源
CSB-YP004959MO1 CSB-EP004959MO1 CSB-BP004959MO1 CSB-MP004959MO1 CSB-EP004959MO1-B	Recombinant Mouse T-lymphocyte activation antigen CD80 (Cd80), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-YP004965MO1 CSB-EP004965MO1 CSB-BP004965MO1 CSB-MP004965MO1 CSB-EP004965MO1-B	Recombinant Mouse T-lymphocyte activation antigen CD86 (Cd86), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF004959MO	Recombinant Mouse T-lymphocyte activation antigen CD80 (Cd80)	in vitro E.coli expression system
CSB-CF004965MO	Recombinant Mouse T-lymphocyte activation antigen CD86 (Cd86)	in vitro E.coli expression system

Cd86 Proteins for Oryctolagus cuniculus (Rabbit)

产品货号	产品名称	来源
CSB-YP004965RB1 CSB-EP004965RB1 CSB-BP004965RB1 CSB-MP004965RB1 CSB-EP004965RB1-B	Recombinant Rabbit T-lymphocyte activation antigen CD86 (CD86), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF004965RB	Recombinant Rabbit T-lymphocyte activation antigen CD86 (CD86)	in vitro E.coli expression system

Cd86 Proteins for Homo sapiens (Human)

产品货号	产品名称	来源
CSB-YP004965HU1 CSB-EP004965HU1 CSB-BP004965HU1 CSB-MP004965HU1 CSB-EP004965HU1-B	Recombinant Human T-lymphocyte activation antigen CD86 (CD86), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF004965HU	Recombinant Human T-lymphocyte activation antigen CD86 (CD86)	in vitro E.coli expression system
CSB-AP005161HU	Recombinant Human T-lymphocyte activation antigen CD86 (CD86), partial (Active)	Mammalian cell