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Cd24

CD24:火热在研新药EXO-CD24,“搭载”外泌体,抵抗COVID-19?

CD24是一种热稳定抗原,属于糖基磷脂酰肌醇(GPI)锚定的细胞表面蛋白。CD24最初被认为是B细胞的标记物,在B细胞分化早期阶段表达,同时对淋巴细胞成熟、神经系统发育及生理状态下的组织更新起到重要的作用。CD24主要表达于造血系统的细胞、神经组织以及一些特定的上皮细胞,同时也见于大多实体肿瘤、炎症组织以及自身免疫性疾病的某些细胞。众多研究发现,CD24在生理与病理状态下具有完全相反的作用——在生理状态下,CD24可抑制组织生长;但在病理状态下,CD24却促进细胞增殖。这些生理特性使得CD24在自身免疫性疾病、炎症、肿瘤等疾病的治疗研究中受到关注。

CUSABIO-哺乳Nanodisc技术平台成功开发CD24活性蛋白。

The Validated Data of CD24-Nanoparticle (Active)

High Purity Validated by SDS-PAGE

Purity was greater than 95% as determined by SDS-PAGE. (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Excellent Bioactivity Validated by Functional ELISA.

Immobilized human CD24 at 2 μg/ml can bind anti-CD24 recombinant Monoclonal Antibody (CSB-RA004902A0HU). The EC50 is 5.409-8.219 ng/ml.


Cd24 Antibodies

Cd24 for Homo sapiens (Human)

Cd24 Proteins

Cd24 Proteins for Homo sapiens (Human)

Cd24 Proteins for Mus musculus (Mouse)