CD70
CD70是CD27配体。它在免疫系统中发挥重要作用,特别是在T细胞的活化和增殖过程中。他的结构包括一个胞外区域、可以与CD27受体结合,一个跨膜区域和一个胞浆区域。CD70的主要功能之一是通过与CD27受体相互作用来调节T细胞的活化和增殖。CD27是T细胞表面的一种分子,当CD70与其结合时,会激活多条信号通路,包括NF-κB、MAPK和PI3K-Akt等信号通路。这些信号通路的激活可以促进细胞增殖、分化和功能发挥,从而加强免疫应答。此外,CD70还可以影响其他免疫细胞,如B细胞和自然杀伤细胞的功能。因此,对其结构、功能和信号通路的深入理解对于免疫调节和相关疾病的治疗具有重要意义。
热销产品
Recombinant Human CD70 antigen (CD70), partial (Active)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced/non-reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD70 at 2 μg/ml can bind Anti-CD70 antibody, the EC50 is 2.414-3.196 ng/mL
CD70 Antibodies
CD70 for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA004954KA01HU | CD70 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA095181 | CD70 Antibody | Human | ELISA,WB |
CSB-PA001476 | CD70 Antibody | Human | WB, ELISA |
CSB-PA615999 | CD70 Antibody | Human | ELISA,IHC |
CSB-PA068483 | CD70 Antibody | Human | ELISA,IHC |
CSB-PA08009A0Rb | CD70 Antibody | Human | ELISA, IF |
CSB-PA08009B0Rb | CD70 Antibody, HRP conjugated | Human | ELISA |
CSB-PA08009C0Rb | CD70 Antibody, FITC conjugated | Human | |
CSB-RA004954MA1HU | CD70 Recombinant Monoclonal Antibody | Human | ELISA |
CD70 Proteins
CD70 Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP004954HU | Recombinant Human CD70 antigen (CD70), partial | Yeast |
CSB-EP004954HU CSB-BP004954HU CSB-MP004954HU CSB-EP004954HU-B |
Recombinant Human CD70 antigen (CD70), partial | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-MP004954HUc9 | Recombinant Human CD70 antigen (CD70), partial | Mammalian cell |
CSB-MP004954HU1 | Recombinant Human CD70 antigen (CD70), partial (Active) | Mammalian cell |
CD70 Proteins for Mus musculus (Mouse)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP004954MO1 CSB-EP004954MO1 CSB-BP004954MO1 CSB-MP004954MO1 CSB-EP004954MO1-B |
Recombinant Mouse CD70 antigen (Cd70), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF004954MO | Recombinant Mouse CD70 antigen (Cd70) | in vitro E.coli expression system |
CD70 Proteins for Sus scrofa (Pig)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP670269PI CSB-EP670269PI CSB-BP670269PI CSB-MP670269PI CSB-EP670269PI-B |
Recombinant Pig CD70 antigen (CD70), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CD70 ELISA Kit
CD70 ELISA Kit for Homo sapiens (Human)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-EL004954HU | Human CD70 antigen(CD70) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 0.039 ng/mL |
CD70 ELISA Kit for Mus musculus (Mouse)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-EL004954MO | Mouse CD70 antigen(CD70) ELISA kit | Request Information |