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CD70

CD70是CD27配体。它在免疫系统中发挥重要作用,特别是在T细胞的活化和增殖过程中。他的结构包括一个胞外区域、可以与CD27受体结合,一个跨膜区域和一个胞浆区域。CD70的主要功能之一是通过与CD27受体相互作用来调节T细胞的活化和增殖。CD27是T细胞表面的一种分子,当CD70与其结合时,会激活多条信号通路,包括NF-κB、MAPK和PI3K-Akt等信号通路。这些信号通路的激活可以促进细胞增殖、分化和功能发挥,从而加强免疫应答。此外,CD70还可以影响其他免疫细胞,如B细胞和自然杀伤细胞的功能。因此,对其结构、功能和信号通路的深入理解对于免疫调节和相关疾病的治疗具有重要意义。

热销产品

Recombinant Human CD70 antigen (CD70), partial (Active)

验证数据

SDS
CSB-MP004954HU1 SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced/non-reduced) with 5% enrichment gel and 15% separation gel.

ELISA
CSB-MP004954HU1 ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD70 at 2 μg/ml can bind Anti-CD70 antibody, the EC50 is 2.414-3.196 ng/mL


CD70 Antibodies

CD70 for Homo sapiens (Human)

CD70 Proteins

CD70 Proteins for Homo sapiens (Human)

CD70 Proteins for Mus musculus (Mouse)

CD70 Proteins for Sus scrofa (Pig)

CD70 ELISA Kit

CD70 ELISA Kit for Homo sapiens (Human)

CD70 ELISA Kit for Mus musculus (Mouse)