ACKR1

ACKR1是人类基因的名称，它提供了合成一种名为Duffy抗原/趋化因子受体的蛋白质（也称为Fy糖蛋白或CD234）的指令。Duffy抗原位于红细胞表面，是以发现该抗原的病人的名字命名的。该基因编码的蛋白质是一种糖基化的膜蛋白，是几种趋化因子的非特异性受体。该蛋白质也是人类疟原虫疟疾病原体Plasmodium vivax、Plasmodium knowlesi和类人猴疟疾原虫Plasmodium cynomolgi的受体。该基因的多态性是Duffy血型系统的基础。
ACKR1 is a gene providing an instruction of making a protein named duffy antigen/chemokine receptor (also known as Fy glycoprotein or CD234) in humans. The Duffy antigen is located on the surface of red blood cells, and is named after the patient in whom it was discovered. The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The protein is also the receptor for the human malarial parasites Plasmodium vivax, Plasmodium knowlesi and simian malarial parasite Plasmodium cynomolgi. Polymorphisms in this gene are the basis of the Duffy blood group system.