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PAM16 Antibody

  • 货号：
    CSB-PA896711DA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: PAM16 antibody at 2μg/ml
      Lane 1: HL60 whole cell lysate
      Lane 2: HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 14 kDa
      Observed band size: 14 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PAM16 Polyclonal antibody
  • Uniprot No.：
    Q9Y3D7
  • 基因名：
    PAM16
  • 别名：
    CGI-136 antibody; MAGMAS antibody; Magmas like protein antibody; Mitochondria associated protein involved in granulocyte macrophage colony stimulating factor signal transduction antibody; Mitochondria-associated granulocyte macrophage CSF-signaling molecule antibody; Mitochondrial import inner membrane translocase subunit TIM16 antibody; PAM16 antibody; Presequence translocase-associated motor 16 homolog (S. cerevisiae) antibody; Presequence translocated-associated motor subunit PAM16 antibody; TIM16 antibody; TIM16_HUMAN antibody; TIMM16 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Mitochondrial import inner membrane translocase subunit TIM16 protein (1-125AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PAM16 Antibody (CSB-PA896711DA01HU)，的标记方式是Non-conjugated。对于PAM16 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA896711DB01HU PAM16 Antibody, HRP conjugated ELISA
    FITC CSB-PA896711DC01HU PAM16 Antibody, FITC conjugated
    Biotin CSB-PA896711DD01HU PAM16 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Regulates ATP-dependent protein translocation into the mitochondrial matrix. Inhibits DNAJC19 stimulation of HSPA9/Mortalin ATPase activity.
  • 基因功能参考文献：
    1. A novel essential role of Magmas is a 'ROS regulatory protein' in the maintenance of cellular redox homeostasis and imparting cytoprotection under oxidative stress. PMID: 25165880
    2. finding of deleterious MAGMAS mutations in an early lethal skeletal dysplasia supports a key role for this mitochondrial protein in the ossification process PMID: 24786642
    3. Magmas protects pituitary cells from apoptosis, suggesting its possible involvement in neoplastic transformation. PMID: 20719856
    4. Magmas expression in prostate cancer. PMID: 15704001
  • 相关疾病：
    Spondylometaphyseal dysplasia, Megarbane-Dagher-Melike type (SMDMDM)
  • 亚细胞定位：
    Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
  • 蛋白家族：
    TIM16/PAM16 family
  • 组织特异性：
    Ubiquitously expressed.
  • 数据库链接：

    HGNC: 29679

    OMIM: 613320

    KEGG: hsa:51025

    STRING: 9606.ENSP00000315693

    UniGene: Hs.730693