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  4. Recombinant Rat Serine/threonine-protein kinase Sgk2 (Sgk2)

Recombinant Rat Serine/threonine-protein kinase Sgk2 (Sgk2)

  • 中文名称：
    大鼠Sgk2重组蛋白
  • 货号：
    CSB-YP837152RA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Sgk2重组蛋白
  • 货号：
    CSB-EP837152RA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Sgk2重组蛋白
  • 货号：
    CSB-EP837152RA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Sgk2重组蛋白
  • 货号：
    CSB-BP837152RA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Sgk2重组蛋白
  • 货号：
    CSB-MP837152RA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Sgk2; Serine/threonine-protein kinase Sgk2; EC 2.7.11.1; Serum/glucocorticoid-regulated kinase 2
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-367
  • 氨基酸序列
    MASSPVGVPS PQPSRANGNI NLGPSANPNA RPTDFDFLKV IGKGNYGKVL LAKRKSDGAF YAVKVLQKKS ILKNKEQSHI MAERNVLLKN VRHPFLVGLR YSFQTPEKLY FVLDYVNGGE LFFHLQREHR FLEPRARFYT AEVASAIGYL HSLNIIYRDL KPENILLDCQ GHVVLTDFGL CKECVEPEET TSTFCGTPEY LAPEVLRKEP YDRAVDWWCL GAVLYEMLHG LPPFFNTDVA QMYENILHQP LQIPGGRTVA ACDLLQGLLH KDQRQRLGSK EDFLDIKNHM FFSPINWDDL YHKRLTPPFN PNVEGPADLK HFDPEFTQEA VSKSIGCTPD TMSSSSGASS AFLGFSYAQD DDDILDS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up-regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase.
  • 基因功能参考文献：
    1. results suggest that pattern of expression, regulation, and role of sgk2 within mammalian kidney are distinct from sgk1 and that sgk2 may play previously unrecognized role in control of transtubular Na(+) transport through NHE3 in the proximal tubule. PMID: 20926631
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Protein kinase superfamily, AGC Ser/Thr protein kinase family
  • 组织特异性：
    Expressed in the proximal tubule and thick ascending limb of the loop of Henle (TALH).
  • 数据库链接：

    KEGG: rno:171497

    STRING: 10116.ENSRNOP00000040718

    UniGene: Rn.3685