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  4. Recombinant Pig C-reactive protein (CRP)

Recombinant Pig C-reactive protein (CRP)

  • 货号：
    CSB-YP005991PI
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP005991PI
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP005991PI-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP005991PI
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP005991PI
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    CRP; PTX1C-reactive protein
  • 种属：
    Sus scrofa (Pig)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    20-222
  • 氨基酸序列
    Q TDMIGKAFVF PKESENSYVS LTARLTKPLT AFTVCLRVYT DLNRDYSLFS YATKTQYNEI LLFRGKTAVY SISVGGADVV FKPHQSSEPM HFCMTWESTS GITELWVDGK PMVRRSLKRG YSLGTQASII LGQEQDAFAG GFEKNQCLVG DIGDVNMWDY VLSPEEINTV YAGGTFSPNV LNWRALRYEM SGEVYVKPQL WP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
  • 基因功能参考文献：
    1. Enhanced external counterpulsation decreased C-reactive protein and increased flow-mediated dilation in hypercholesterolemia. PMID: 22681602
    2. serum C-reactive protein correlates with macrophage accumulation and coronary artery disease in hypercholesterolemic pigs PMID: 12754176
    3. CRP inhibits endothelium-dependent NO-mediated dilation in coronary arterioles by producing superoxide from NAD(P)H oxidase via p38 kinase activation. PMID: 15718491
    4. The present study shows that elevated levels of serum CRP and IL-10 were associated with porcine circovirus type 2-infected piglets that subsequently developed severe PMWS. (postweaning multisystemic wasting syndrome) PMID: 16817761
    5. These data suggest that CRP might play a pathogenic role in the development of myointimal hyperplasia in polytetrafluoroethylene grafts. PMID: 17510097
    6. myocardial infarction induced proinflammatory gene and protein expression in peripheral blood mononuclear cells of tissue factor cyclo-oxygenase-2, monocyte chemoattractant protein-1 and CRP PMID: 19036073
    7. CRP stimulates superoxide production and the subsequent formation of peroxynitrite from basal released nitric oxide compromises PGI(2) synthesis. PMID: 19410579
    8. Data show that during posttranplant obliterative bronchiolitis development, CRP is localized in inflammatory cells, myofibroblasts and endothelial cells probably as a part of the local inflammatory response. PMID: 19503785

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Pentraxin family
  • 组织特异性：
    Found in plasma.
  • 数据库链接：

    KEGG: ssc:396842

    STRING: 9823.ENSSSCP00000029570

    UniGene: Ssc.16157