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  4. Recombinant Mouse TMF-regulated nuclear protein 1 (Trnp1)

Recombinant Mouse TMF-regulated nuclear protein 1 (Trnp1)

  • 货号：
    CSB-YP773949MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP773949MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP773949MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP773949MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP773949MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Trnp1
  • Uniprot No.：
  • 别名：
    Trnp1; Trnp; TMF-regulated nuclear protein 1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-223
  • 氨基酸序列
    MPGCRISACG PGAQEGTAEP GSPPPPPREP LPSLQPPSPS PTSTPTPTKS PPLPEAAETP VEGQELQRWR QGASGGSGGA GPAGIAGAAA GAGGRALELA EARRRLLEVE GRRRLVSELE SRVLQLHRVF LAAELRLAHR AESLSRLSGG VAQAELYLAA HGSRLKKGAR RGRRGRPPAL LASALGLGSC VPWGAGRLRR GQGPEPDSPF RRSPPRGPAS PQR
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    DNA-binding factor that regulates the expression of a subset of genes and plays a key role in tangential, radial, and lateral expansion of the brain neocortex. Regulates neural stem cells proliferation and the production of intermediate neural progenitors and basal radial glial cells affecting the process of cerebral cortex gyrification. May control the proliferation rate of cells by regulating their progression through key cell-cycle transition points.
  • 基因功能参考文献：
    1. Data suggest that neurons in mouse brain exhibit DNA sequence encoding protein precursor, proMexneurin, that contains three peptide sequences: Mexneurin-1 (an endomorphin1-like peptide), Mexneurin-2 (an endomorphin1-like peptide), and Mexneurin-3 (peptide which appears to be unrelated to endomorphins); neurons exhibit expression of proMexneurin mRNA throughout mouse brain. PMID: 28504339
    2. Study identified Trnp1 as a regulator of mammalian brain development and as a key factor controlling neocortical expansion. Trnp1 levels have striking effects on tangential, radial, and lateral expansion of the cerebral cortex. PMID: 23622239
  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Expressed in brain and kidney (at protein level). Also detected in spleen and intestine.
  • 数据库链接：

    KEGG: mmu:69539

    STRING: 10090.ENSMUSP00000129613

    UniGene: Mm.151594