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  4. Recombinant Mouse Proline-rich protein 5-like (Prr5l)

Recombinant Mouse Proline-rich protein 5-like (Prr5l)

  • 中文名称：
    小鼠Prr5l重组蛋白
  • 货号：
    CSB-YP381792MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Prr5l重组蛋白
  • 货号：
    CSB-EP381792MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Prr5l重组蛋白
  • 货号：
    CSB-EP381792MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Prr5l重组蛋白
  • 货号：
    CSB-BP381792MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Prr5l重组蛋白
  • 货号：
    CSB-MP381792MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Prr5l
  • Uniprot No.：
  • 别名：
    Prr5l; Protor2; Proline-rich protein 5-like; Protein observed with Rictor-2; Protor-2
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-370
  • 氨基酸序列
    MTRGLAPLLP IEFHKMGSFR RPRPRFMSSP VLSELPRFQA ARQALQLSSN SAWNSVQTAV INVFKGGGLQ SNELYALNES IRRLLKSELG SFITDYFQNQ LLAKGLSFVE EKIKLCEGDN RIEVLAEVWD HFFTETLPTL QAIFYPVQGQ ELTIRQISLL GFRDLVLLKV KLGDVLLLAQ SKLPSSVIQM LLILQSVHEP TGPSEGYLQL EELVKQVVSP FLSISGDRSC SGPTYSLARR HSRVRPKVTV LNYASLMTTV GRPLNEMVLT PLTEQEGEAY LEKCGSVRRH TVANAHSDIQ LLAMATMMHS GLGEEAGGED KHLLLPPSFP PPHRQCSSEP SILDSPDELE LEDVASGSQE DSELNCASLS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Associates with the mTORC2 complex that regulates cellular processes including survival and organization of the cytoskeleton. Regulates the activity of the mTORC2 complex in a substrate-specific manner preventing for instance the specific phosphorylation of PKCs and thereby controlling cell migration. Plays a role in the stimulation of ZFP36-mediated mRNA decay of several ZFP36-associated mRNAs, such as TNF-alpha and GM-CSF, in response to stress. Required for ZFP36 localization to cytoplasmic stress granule (SG) and P-body (PB) in response to stress.
  • 基因功能参考文献：
    1. PRR5L degradation promotes mTORC2-mediated PKC-delta phosphorylation and cell migration downstream of Galpha12 in fibroblasts and pulmonary fibrosis. PMID: 22609986
  • 蛋白家族：
    PROTOR family
  • 数据库链接：

    KEGG: mmu:72446

    STRING: 10090.ENSMUSP00000042167

    UniGene: Mm.24138