IL17A

白细胞介素- 17a是一种由IL17A基因编码的人类蛋白质。是IL17RA和IL17RC的配体。IL17家族是一类由CD4+T细胞分泌的促炎细胞因子，包括IL17A在内共计6个成员。IL17A在染色体6p12.2,由Il17R传递信号，可以诱导多种炎症因子表达，介导炎症反应加速机体修复，以发挥保护作用。在慢性炎症情况下，IL17A通过激活NF-ҠB、JAK/STAT等信号通路，持续促进细胞因子、趋化因子和基质金属蛋白酶等的释放及免疫细胞浸润，促进疾病的发生发展。此外，IL17A还可以促进多种血管生成调节因子的分泌，促进肿瘤血管的形成和转移。

热销产品

Recombinant Human Interleukin-17A(IL17A)(T26A) (Active) CSB-BP624104HU(M)

验证数据

High Purity Validated by SDS-PAGE

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Excellent Bioactivity Validated by Functional ELISA

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human IL17A at 2 μg/ml can bind Anti-IL17A recombinant antibody (CSB-RA624104MA1HU), the EC₅₀ is 1.818-2.170 ng/mL.

IL17A Antibody

IL17A Protein

IL17A ELISA Kit

IL17A Antibodies

IL17A for Homo sapiens (Human)

产品货号	产品名称	种属反应性	应用类型
CSB-PA011597GA01HU	IL17A Antibody	Human	ELISA,IHC
CSB-PA06659A0Rb	IL17A Antibody	Human	ELISA, IHC, IF
CSB-PA06659B0Rb	IL17A Antibody, HRP conjugated	Human	ELISA
CSB-PA06659C0Rb	IL17A Antibody, FITC conjugated	Human
CSB-PA06659D0Rb	IL17A Antibody, Biotin conjugated	Human	ELISA

IL17A Proteins

IL17A Proteins for Homo sapiens (Human)

产品货号	产品名称	来源
CSB-YP624104HU CSB-EP624104HU CSB-BP624104HU CSB-MP624104HU CSB-EP624104HU-B	Recombinant Human Interleukin-17A (IL17A)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP001851HU	Recombinant Human Interleukin-17A protein (IL17A)	E.Coli
CSB-AP004331HU	Recombinant Human Interleukin-17A (IL17A) (Active)	E.coli
CSB-AP004341HU	Recombinant Human Interleukin-17A (IL17A) (Active)	Mammalian cell
CSB-AP004701HU	Recombinant Human IL17A & IL17F Heterodimer Protein (Active)	Mammalian cell

IL17A Proteins for Rattus norvegicus (Rat)

产品货号	产品名称	来源
CSB-YP717213RA CSB-BP717213RA CSB-MP717213RA CSB-EP717213RA-B	Recombinant Rat Interleukin-17A (Il17a)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL17A Proteins for Mus musculus (Mouse)

产品货号	产品名称	来源
CSB-YP720298MO CSB-EP720298MO CSB-BP720298MO CSB-MP720298MO CSB-EP720298MO-B	Recombinant Mouse Interleukin-17A (Il17a)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP004781MO	Recombinant Mouse Interleukin-17A (Il17a), partial (Active)	Mammalian cell

IL17A Proteins for Bos taurus (Bovine)

产品货号	产品名称	来源
CSB-YP724243BO CSB-EP724243BO CSB-BP724243BO CSB-MP724243BO CSB-EP724243BO-B	Recombinant Bovine Interleukin-17A (IL17A)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL17A Proteins for Sus scrofa (Pig)

产品货号	产品名称	来源
CSB-YP736792PI CSB-BP736792PI CSB-MP736792PI CSB-EP736792PI-B	Recombinant Pig Interleukin-17A (IL17A)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli