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  4. Recombinant Mouse IQ domain-containing protein G (Iqcg)

Recombinant Mouse IQ domain-containing protein G (Iqcg)

  • 中文名称：
    小鼠Iqcg重组蛋白
  • 货号：
    CSB-YP800344MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Iqcg重组蛋白
  • 货号：
    CSB-EP800344MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Iqcg重组蛋白
  • 货号：
    CSB-EP800344MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Iqcg重组蛋白
  • 货号：
    CSB-BP800344MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Iqcg重组蛋白
  • 货号：
    CSB-MP800344MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Iqcg
  • Uniprot No.：
  • 别名：
    Iqcg; Drc9Dynein regulatory complex protein 9; IQ domain-containing protein G
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-419
  • 氨基酸序列
    MDEEEVEVVE SPSEVLQPEV TVVVTGEPPE AAEEDLDYEE EEETSPEVIE TLSLLDVLRV SAVMEDVIDQ LSILGYIIPV QYERRQSLTQ KASHEGASMI TTTPKKSTSL LTKEKSMMAE NKQRGQDFTF KKPTKQTMMT LETLKKIQND RQYFSDVIAN AMMEMQDSGS FTSLLKALGK ERDSKMNFHD VITREEKGRK QIKTLQKQLL DVKRERQMQV QNGNEYIAHL RDQLQEMKAK TNLENLYMKR NAELQISQTQ KKCNRAEELL LEEIEKLRMK TEEENRVHTE IEMFLKKQQQ KLEEKLEFWM EKFDKDTEAK QNELNALKAA KASDLVHLQD LAKMIREYEQ VIIEDRIEKE KTRKKLEQDD LELRSIVKLQ AWWRGSVVRK EIGNFKMPKK DKDDSKDSKG KEKEKRRKK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Binds calmodulin when cellular Ca(2+) levels are low and thereby contributes to the regulation of calcium and calmodulin-dependent protein kinase IV (CAMK4) activity; contributes to the regulation of CAMK4 signaling cascades. Required for normal axoneme assembly in sperm flagella, normal sperm tail formation and for male fertility.
  • 基因功能参考文献：
    1. Iqcg is specifically required for spermiogenesis in mammals PMID: 24849454
    2. Loss of Iqcg disrupts spermiogenesis such that tail formation either occurs incompletely or breaks apart from the sperm heads. PMID: 24362311
  • 亚细胞定位：
    Cytoplasm. Cell projection, cilium, flagellum. Cell projection, cilium. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, flagellum axoneme.
  • 蛋白家族：
    DRC9 family
  • 组织特异性：
    Detected in testis. Also detected in oviduct (at protein level). Detected in testis. Also detected in oviduct and trachea.
  • 数据库链接：

    KEGG: mmu:69707

    STRING: 10090.ENSMUSP00000110752

    UniGene: Mm.227918