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  4. Recombinant Human Tubulin-specific chaperone cofactor E-like protein (TBCEL)

Recombinant Human Tubulin-specific chaperone cofactor E-like protein (TBCEL)

  • 货号：
    CSB-YP722183HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP722183HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP722183HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP722183HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    TBCEL
  • Uniprot No.：
  • 别名：
    EL; Leucine-rich repeat-containing protein 35; LRRC35; TBCEL; TBCEL_HUMAN; Tubulin folding cofactor E-like; Tubulin-specific chaperone cofactor E-like protein
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-424
  • 氨基酸序列
    MDQPSGRSFM QVLCEKYSPE NFPYRRGPGM GVHVPATPQG SPMKDRLNLP SVLVLNSCGI TCAGDEKEIA AFCAHVSELD LSDNKLEDWH EVSKIVSNVP QLEFLNLSSN PLNLSVLERT CAGSFSGVRK LVLNNSKASW ETVHMILQEL PDLEELFLCL NDYETVSCPS ICCHSLKLLH ITDNNLQDWT EIRKLGVMFP SLDTLVLANN HLNAIEEPDD SLARLFPNLR SISLHKSGLQ SWEDIDKLNS FPKLEEVRLL GIPLLQPYTT EERRKLVIAR LPSVSKLNGS VVTDGEREDS ERFFIRYYVD VPQEEVPFRY HELITKYGKL EPLAEVDLRP QSSAKVEVHF NDQVEEMSIR LDQTVAELKK QLKTLVQLPT SNMLLYYFDH EAPFGPEEMK YSSRALHSFG IRDGDKIYVE SKTK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts as a regulator of tubulin stability.
  • 基因功能参考文献：
    1. Leucine rich repeat containing 35 (E-like) is a novel regulator of tubulin stability with overexpression causing depolymerization of microtubules and suppression resulting in an increase in the number of stable microtubules. PMID: 15728251
    2. Depletion of Op18 by means of RNA interference increased the susceptibility of tubulin to TBCE or E-like mediated disruption, while overexpressed Op18 exerted a tubulin-protective effect. PMID: 18262179
  • 亚细胞定位：
    Cytoplasm, cytoskeleton.
  • 组织特异性：
    Abundantly expressed in testis, but is also present in several tissues at a much lower level.
  • 数据库链接：

    HGNC: 28115

    OMIM: 610451

    KEGG: hsa:219899

    STRING: 9606.ENSP00000403925

    UniGene: Hs.504136