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  4. Recombinant Human Solute carrier organic anion transporter family member 3A1 (SLCO3A1), partial

Recombinant Human Solute carrier organic anion transporter family member 3A1 (SLCO3A1), partial

  • 中文名称：
    人SLCO3A1重组蛋白
  • 货号：
    CSB-YP883432HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SLCO3A1重组蛋白
  • 货号：
    CSB-EP883432HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SLCO3A1重组蛋白
  • 货号：
    CSB-EP883432HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SLCO3A1重组蛋白
  • 货号：
    CSB-BP883432HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SLCO3A1重组蛋白
  • 货号：
    CSB-MP883432HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SLCO3A1
  • Uniprot No.：
  • 别名：
    SLCO3A1; OATP3A1; OATPD; SLC21A11; Solute carrier organic anion transporter family member 3A1; OATP3A1; Organic anion transporter polypeptide-related protein 3; OATP-RP3; OATPRP3; Organic anion-transporting polypeptide D; OATP-D; PGE1 transporter; Sodium-independent organic anion transporter D; Solute carrier family 21 member 11
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Mediates the Na(+)-independent transport of organic anions such as estrone-3-sulfate. Mediates transport of prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II, BQ-123 and vasopressin, but not DPDPE (a derivative of enkephalin lacking an N-terminal tyrosine residue), estrone-3-sulfate, taurocholate, digoxin nor DHEAS.
  • 基因功能参考文献：
    1. OATP3A1 functions as a bile acid efflux transporter that is up-regulated as an adaptive response to cholestasis. PMID: 30063921
    2. SLCO3A1, a novel Crohn's disease-associated gene, mediates inflammatory processes in intestinal epithelial cells through NF-kappaB transcription activation. PMID: 24945726
    3. Single nucleotide polymorhpisms of SLCO3A1 were associated with nicotine dependence. PMID: 22377092
    4. OATP-D plays an important role in translocating prostaglandins in specialized tissues and cells. PMID: 14631946
    5. Further evidence is provided for the involvement of OATPs in oligopeptide transport. OATP3A1 variants might be involved in the regulation of extracellular vasopressin concentration in human brain. PMID: 16971491

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  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Organo anion transporter (TC 2.A.60) family
  • 组织特异性：
    Ubiquitous. Highly expressed in spleen and leukocytes. Generally the expression of isoform 1 is higher than that of isoform 2. Isoform 2 is particularly abundant in testis and brain. In testis, isoform 1 is detected in spermatogonia at different stages an
  • 数据库链接：

    HGNC: 10952

    OMIM: 612435

    KEGG: hsa:28232

    STRING: 9606.ENSP00000320634

    UniGene: Hs.311187