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SLCO3A1 Antibody

  • 货号：
    CSB-PA883432LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA883432LA01HU at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA883432LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SLCO3A1 Polyclonal antibody
  • Uniprot No.：
    Q9UIG8
  • 基因名：
    SLCO3A1
  • 别名：
    SLCO3A1 antibody; OATP3A1 antibody; OATPD antibody; SLC21A11 antibody; Solute carrier organic anion transporter family member 3A1 antibody; OATP3A1 antibody; Organic anion transporter polypeptide-related protein 3 antibody; OATP-RP3 antibody; OATPRP3 antibody; Organic anion-transporting polypeptide D antibody; OATP-D antibody; PGE1 transporter antibody; Sodium-independent organic anion transporter D antibody; Solute carrier family 21 member 11 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Solute carrier organic anion transporter family member 3A1 protein (439-539AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SLCO3A1 Antibody (CSB-PA883432LA01HU)，的标记方式是Non-conjugated。对于SLCO3A1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA883432LB01HU SLCO3A1 Antibody, HRP conjugated ELISA
    FITC CSB-PA883432LC01HU SLCO3A1 Antibody, FITC conjugated
    Biotin CSB-PA883432LD01HU SLCO3A1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Mediates the Na(+)-independent transport of organic anions such as estrone-3-sulfate. Mediates transport of prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II, BQ-123 and vasopressin, but not DPDPE (a derivative of enkephalin lacking an N-terminal tyrosine residue), estrone-3-sulfate, taurocholate, digoxin nor DHEAS.
  • 基因功能参考文献：
    1. OATP3A1 functions as a bile acid efflux transporter that is up-regulated as an adaptive response to cholestasis. PMID: 30063921
    2. SLCO3A1, a novel Crohn's disease-associated gene, mediates inflammatory processes in intestinal epithelial cells through NF-kappaB transcription activation. PMID: 24945726
    3. Single nucleotide polymorhpisms of SLCO3A1 were associated with nicotine dependence. PMID: 22377092
    4. OATP-D plays an important role in translocating prostaglandins in specialized tissues and cells. PMID: 14631946
    5. Further evidence is provided for the involvement of OATPs in oligopeptide transport. OATP3A1 variants might be involved in the regulation of extracellular vasopressin concentration in human brain. PMID: 16971491

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  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Organo anion transporter (TC 2.A.60) family
  • 组织特异性：
    Ubiquitous. Highly expressed in spleen and leukocytes. Generally the expression of isoform 1 is higher than that of isoform 2. Isoform 2 is particularly abundant in testis and brain. In testis, isoform 1 is detected in spermatogonia at different stages an
  • 数据库链接：

    HGNC: 10952

    OMIM: 612435

    KEGG: hsa:28232

    STRING: 9606.ENSP00000320634

    UniGene: Hs.311187