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  4. Recombinant Human E3 ubiquitin-protein ligase ZNF645 (ZNF645)

Recombinant Human E3 ubiquitin-protein ligase ZNF645 (ZNF645)

  • 中文名称：
    人ZNF645重组蛋白
  • 货号：
    CSB-YP836684HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人ZNF645重组蛋白
  • 货号：
    CSB-EP836684HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人ZNF645重组蛋白
  • 货号：
    CSB-EP836684HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人ZNF645重组蛋白
  • 货号：
    CSB-BP836684HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人ZNF645重组蛋白
  • 货号：
    CSB-MP836684HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ZNF645
  • Uniprot No.：
  • 别名：
    CBLL2; ZNF645E3 ubiquitin-protein ligase CBLL2; EC 2.3.2.27; Cbl proto-oncogene-like protein 2; RING-type E3 ubiquitin transferase ZNF645; Zinc finger protein 645; c-Cbl-like protein 2
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-425
  • 氨基酸序列
    MNKMPAGEQE CEYNKEGKYY SKGVKLVRKK KKIPGYRWGD IKINIIGEKD DLPIHFCDKC DLPIKIYGRI IPCKHAFCYH CANLYDKVGY KVCPRCRYPV LRIEAHKRGS VFMCSIVQQC KRTYLSQKSL QAHIKRRHKR ARKQVTSASL EKVRPHIAPP QTEISDIPKR LQDRDHLSYI PPEQHTMVSL PSVQHMLQEQ HNQPHKDIQA PPPELSLSLP FPIQWETVSI FTRKHGNLTV DHIQNNSDSG AKKPTPPDYY PECQSQPAVS SPHHIIPQKQ HYAPPPSPSS PVNHQMPYPP QDVVTPNSVR SQVPALTTTY DPSSGYIIVK VPPDMNSPPL RAPQSQNGNP SASEFASHHY NLNILPQFTE NQETLSPQFT QTDAMDHRRW PAWKRLSPCP PTRSPPPSTL HGRSHHSHQR RHRRY
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. May operate on tyrosine-phosphorylated SRC substrates.
  • 基因功能参考文献：
    1. A novel RING finger protein, ZNF645, which is expressed specifically in human testis and sperm and has E3 ubiquitin ligase activity. PMID: 20657603
  • 亚细胞定位：
    Cytoplasm.
  • 组织特异性：
    Exclusively expressed in testis and sperm, including spermatocytes, round and elongated spermatids, and Leydig cells.
  • 数据库链接：

    HGNC: 26371

    KEGG: hsa:158506

    STRING: 9606.ENSP00000323348

    UniGene: Hs.132485